2. Gene
  3. NMRK2 - nicotinamide riboside kinase 2 Gene

NMRK2 - nicotinamide riboside kinase 2 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：烟酰胺核苷激酶 2

种属: Homo sapiens

同用名: MIBP; NRK2; ITGB1BP3

基因 ID: 27231 | 基因类型: protein coding

关于 NMRK2

Cytogenetic location: 19p13.3 Genomic coordinates (GRCh38): 19:3,933,069-3,942,416 (from NCBI)

This gene has 5 transcripts (splice variants), 264 orthologues and 3 paralogues. Restricted expression toward heart (RPKM 167.4).

功能概要

启用核糖基烟酰胺激酶活性和核糖基烟酸激酶活性。预计参与 NAD 代谢过程。预计在成肌细胞分化的负调节上游或负调节内起作用。位于核质和质膜中。 [由基因组资源联盟提供，2022 年 4 月]

Enables ribosylnicotinamide kinase activity and ribosylnicotinate kinase activity. Predicted to be involved in NAD metabolic process. Predicted to act upstream of or within negative regulation of myoblast differentiation. Located in nucleoplasm and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

NMRK2 基因产物(5)

mRNA Protein Name
NM_001289117.2 NP_001276046.1 nicotinamide riboside kinase 2 isoform 1
NM_001375467.2 NP_001362396.1 nicotinamide riboside kinase 2 isoform 3
NM_001375468.2 NP_001362397.1 nicotinamide riboside kinase 2 isoform 4
NM_001375469.2 NP_001362398.1 nicotinamide riboside kinase 2 isoform 5
NM_170678.3 NP_733778.1 nicotinamide riboside kinase 2 isoform 2
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
12809483 GOA
enables ribosylnicotinamide kinase activity EXP
EXP: 通过实验结果推断
15137942 GOA
enables ribosylnicotinate kinase activity EXP
EXP: 通过实验结果推断
15137942 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

NMRK2 蛋白结构

AAA_18

AAA_18: AAA domain (5 - 143)

  • 0
  • 100
  • 200
  • 230 a.a.
蛋白主名 其他名称

nicotinamide riboside kinase 2

NRK 2

关联疾病

疾病名称 别名
Muscular Dystrophy, Congenital, Due To Integrin Alpha-7 Deficiency

Congenital Muscular Dystrophy Due To Integrin Alpha-7 Deficiency

Muscular Dystrophy, Congenital, Due To Itga7 Deficiency

Congenital Muscular Dystrophy With Integrin Alpha-7 Deficiency

Congenital Muscular Dystrophy With Itga7 Deficiency

Congenital Myopathy Due To Integrin Alpha-7 Deficiency

Myopathy, Congenital, Due To Integrin Alpha-7 Deficiency

Muscular Dystrophy Congenital Due To Integrin Alpha-7 Deficiency

MDCI

Dystrophy, Muscular, Congenital, Due To Integrin Alpha-7 Deficiency
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS09387 NMRK2 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus NMRK2 VGNC VGNC:106842
Mus musculus NMRK2 MGD MGI:1916814
Rattus norvegicus NMRK2 RGD RGD:6486791
Macaca mulatta NMRK2 VGNC VGNC:75203
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