2. Gene
  3. Tnfrsf12a - tumor necrosis factor receptor superfamily, member 12a Gene

Tnfrsf12a - tumor necrosis factor receptor superfamily, member 12a Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Fn14; HPIP; TweakR; TWEAK-R

基因 ID: 27279 | 基因类型: protein coding

关于 Tnfrsf12a

功能概要

Involved in regulation of angiogenesis. Acts upstream of or within extrinsic apoptotic signaling pathway; positive regulation of axon extension; and substrate-dependent cell migration, cell attachment to substrate. Located in cell surface; plasma membrane; and ruffle. Is expressed in several structures, including adrenal medulla; genitourinary system; heart; limb long bone; and molar. Orthologous to human TNFRSF12A (TNF Receptor Superfamily member 12A). [provided by Alliance of Genome Resources, Apr 2022]

Tnfrsf12a 基因产物(2)

mRNA Protein Name
NM_001161746.1 NP_001155218.1 tumor necrosis factor receptor superfamily member 12A isoform 2 precursor
NM_013749.2 NP_038777.2 tumor necrosis factor receptor superfamily member 12A isoform 1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
14573547 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cell adhesion IDA
IDA: 通过直接分析推断
10551889 MGI
acts upstream of or within extrinsic apoptotic signaling pathway IDA
IDA: 通过直接分析推断
12821115 MGI
acts upstream of or within positive regulation of axon extension IDA
IDA: 通过直接分析推断
14573547 MGI
involved in regulation of angiogenesis IDA
IDA: 通过直接分析推断
11728344 MGI
acts upstream of or within substrate-dependent cell migration, cell attachment to substrate IDA
IDA: 通过直接分析推断
10551889 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell surface IDA
IDA: 通过直接分析推断
12821115 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
10551889 MGI
located in ruffle IDA
IDA: 通过直接分析推断
14573547 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

tumor necrosis factor receptor superfamily member 12A

FGF-inducible 14

fibroblast growth factor-inducible immediate-early response protein 14

fibroblast growth factor-regulated protein 2

tweak-receptor

type I transmembrane protein Fn14

重组 Tnfrsf12a 蛋白

目录号 产品名 蛋白编号 纯度
HY-P72435 TNFRSF12A Protein, Mouse (HEK293, Fc) Q9CR75 (E28-W79) ≥95%
HY-P700229AF Animal-Free TNFRSF12A Protein, Mouse (His) Q9CR75 (S94-H249) ≥95%

相关产品

Clinical Phase
抗体抑制剂 (1)
目录号 产品名 作用方式
纯度 Phase
HY-P99361 Enavatuzumab Inhibitor ≥95.0% Phase 1
Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS14803 TNFRSF12A Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tnfrsf12a NCBI NCBI:51330
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