RBMS3 - RNA binding motif single stranded interacting protein 3 Gene

中文名称：RNA 结合基序单链相互作用蛋白 3

种属: Homo sapiens

关于 RBMS3

功能概要

该基因编码属于 c-Myc 基因单链结合蛋白家族的 RNA 结合蛋白。这些蛋白质的特点是存在两组核糖核蛋白共有序列 (RNP-CS) ，其中包含保守基序 RNP1 和 RNP2，最初在 RNA 结合蛋白中描述，并且是 DNA 结合所必需的。这些蛋白质涉及多种功能，如 DNA 复制、基因转录、细胞周期进程和细胞凋亡。编码的蛋白质因其与 alpha2 (I) 胶原启动子的上游元素的结合而被分离。这种蛋白质主要定位于细胞质的观察表明它可能参与细胞质功能，例如控制 RNA 代谢，而不是转录。已为该基因发现编码不同亚型的多个可变剪接转录物变体。[RefSeq 提供，2010 年 4 月]

This gene encodes an RNA-binding protein that belongs to the c-Myc gene single-strand binding protein family. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, originally described in RNA binding proteins, and required for DNA binding. These proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and Apoptosis. The encoded protein was isolated by virtue of its binding to an upstream element of the alpha2(I) collagen promoter. The observation that this protein localizes mostly in the cytoplasm suggests that it may be involved in a cytoplasmic function such as controlling RNA metabolism, rather than transcription. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010]