AMY1A - amylase alpha 1A Gene

中文名称：淀粉酶α1A

种属: Homo sapiens

同用名: AMY1

基因 ID: 276 | 基因类型: protein coding

关于 AMY1A

Cytogenetic location: 1p21.1 Genomic coordinates (GRCh38): 1:103,655,519-103,664,554 (from NCBI)

This gene has 4 transcripts (splice variants), 192 orthologues and 7 paralogues. Restricted expression toward salivary gland (RPKM 4834.2).

功能概要

淀粉酶是分泌型蛋白质，可水解寡糖和多糖中的 1,4-α-葡萄糖苷键，从而催化消化膳食淀粉和糖原的第一步。人类基因组有一组淀粉酶基因，它们在唾液腺或胰腺中高水平表达。该基因编码唾液腺产生的淀粉酶同工酶。可变剪接导致编码相同蛋白质的多个转录变体。[RefSeq 提供，2008 年 7 月]

Amylases are secreted proteins that hydrolyze 1,4-alpha-glucoside bonds in oligosaccharides and Polysaccharides, and thus catalyze the first step in digestion of dietary starch and glycogen. The human genome has a cluster of several amylase genes that are expressed at high levels in either salivary gland or pancreas. This gene encodes an amylase isoenzyme produced by the salivary gland. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]

AMY1A 基因产物(2)

mRNA	Protein	Name
NM_001008221.1	NP_001008222.1	alpha-amylase 1A precursor
NM_004038.4	NP_004029.2	alpha-amylase 1A precursor

基因本体论

分子功能
生物过程
细胞组分

分子功能 GO 注释	逻辑证据	参考文献	来源
enables alpha-amylase activity	IDA IDA: 通过直接分析推断	12527308	GOA
enables calcium ion binding	IDA IDA: 通过直接分析推断	12527308	GOA
enables chloride ion binding	IDA IDA: 通过直接分析推断	12527308	GOA

生物过程 GO 注释	逻辑证据	参考文献	来源
involved in oligosaccharide metabolic process	IDA IDA: 通过直接分析推断	12527308	GOA

细胞组分 GO 注释	逻辑证据	参考文献	来源
located in extracellular space	IDA IDA: 通过直接分析推断	15299664	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

AMY1A 蛋白结构

Alpha-amylase

Alpha-amylase_C

0
100
200
300
400
511 a.a.

蛋白主名

其他名称

alpha-amylase 1A

1,4-alpha-D-glucan glucanohydrolase 1

关联疾病

疾病名称

别名

Dental Caries

Dental Caries Extending Into Pulp	Dental Caries Of Smooth Surface
Dental Caries Pit And Fissure	Smooth Surface Dental Caries
Dental Decay	Carious Teeth
Dental Cavity	Saprodontia
Teeth Decayed	Tooth Caries
Tooth Decay

Panic Disorder

Panic Anxiety Syndrome	Panic
Panic Disorder 1	Episodic Paroxysmal Anxiety Disorder

Alveolar Periostitis

Dry Socket	Alveolitis Of Jaw
Dry Tooth Socket	Alveolar Pyorrhea
Alveolar Osteitis	Alveolitis Sicca Dolorosa
Alveolodental Periostitis

Anxiety

Anxiety Disorder	Anxiety Disorders
Anxiety State	Anxieties
Anxiety Neurosis

Sick Building Syndrome

Avoidant Personality Disorder

Anxious Personality Disorder

Personality Disorders

Bruxism

Sleep Bruxism	Sleep-Related Bruxism
Bruxism - Teeth Grinding	Grinding Teeth
Sleep Related Bruxism	Teeth Grinding
Sleep Related Teeth Grinding

Phobic Disorder

Phobic Disorders

Phobic Anxiety Disorder

Social Phobia

Phobia, Social	Phobia Social
Phobic Anxiety Disorder

Post-Traumatic Stress Disorder

PTSD	Traumatic Neurosis
Post Traumatic Stress Disorder	Stress Disorders, Post-Traumatic
Posttraumatic Stress Disorder	Ptsd - [Post Traumatic Stress Disorder]
Trauma-Related Disorders

Stereotypic Movement Disorder

Stereotypy Habit Disorder	Stereotyped Repetitive Movements
Stereotyped Disorder	Stereotypes Nos
Stereotype Habit Disorder

MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。	站点地图隐私声明
沪ICP备15051369号-4 上海工商沪公网安备31011502019417 沪(浦)应急管危经许[2021]201709(QFYS) 营业执照（三证合一）
Copyright © 2013-2025 MedChemExpress. All Rights Reserved.

AMY1A - amylase alpha 1A Gene

关于 AMY1A

功能概要

AMY1A 基因产物(2)

AMY1A 蛋白结构

关联疾病

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

姓名
邮箱 *

Sorry, but the email address you supplied was invalid.

AMY1A - amylase alpha 1A Gene

关于 AMY1A

功能概要

AMY1A 基因产物(2)

AMY1A 蛋白结构

关联疾病

相关产品

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z