2. Gene
  3. SLCO4A1 - solute carrier organic anion transporter family member 4A1 Gene

SLCO4A1 - solute carrier organic anion transporter family member 4A1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：溶质载体有机阴离子转运蛋白家族成员 4A1

种属: Homo sapiens

同用名: POAT; OATP1; OATPE; OATP-E; OATP4A1; OATPRP1; SLC21A12

基因 ID: 28231 | 基因类型: protein coding

关于 SLCO4A1

Cytogenetic location: 20q13.33 Genomic coordinates (GRCh38): 20:62,642,503-62,690,740 (from NCBI)

This gene has 9 transcripts (splice variants), 208 orthologues and 10 paralogues. Ubiquitous expression in esophagus (RPKM 2.4), endometrium (RPKM 1.6) and 23 other tissues.

功能概要

预计可启用不依赖钠的有机阴离子跨膜转运蛋白活性和甲状腺激素跨膜转运蛋白活性。预计参与不依赖钠的有机阴离子转运。预测位于质膜中。预计是质膜的组成部分。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable sodium-independent organic anion transmembrane transporter activity and thyroid hormone transmembrane transporter activity. Predicted to be involved in sodium-independent organic anion transport. Predicted to be located in plasma membrane. Predicted to be integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

SLCO4A1 基因产物(1)

mRNA Protein Name
NM_016354.4 NP_057438.3 solute carrier organic anion transporter family member 4A1

SLCO4A1 蛋白结构

OATP

OATP: Organic Anion Transporter Polypeptide (OATP) family (104 - 664)

Kazal_2

Kazal_2: Kazal-type serine protease inhibitor domain (510 - 553)

  • 0
  • 200
  • 400
  • 600
  • 722 a.a.
蛋白主名 其他名称

solute carrier organic anion transporter family member 4A1

OATP-RP1

关联疾病

疾病名称 别名
Primary Hypertrophic Osteoarthropathy

Pachydermoperiostosis Syndrome

Osteoarthropathy, Primary Hypertrophic

Pachydermoperiostosis Of Nail

Idiopathic Hypertrophic Osteoarthropathy

Pho
Myasthenic Syndrome, Congenital, 1b, Fast-Channel

CMS1B

Congenital Myasthenic Syndrome 1b

Myasthenic Syndrome, Congenital, Fast-Channel

Congenital Myasthenic Syndrome 1b, Fast-Channel

Fccms

Myasthenic Syndrome, Fast-Channel Congenital

Myasthenic Syndrome, Congenital, Type 1b, Fast-Channel

Congenital Myasthenic Syndrome Ib
Intrahepatic Cholestasis Of Pregnancy

Recurrent Intrahepatic Cholestasis Of Pregnancy

Gravidic Intrahepatic Cholestasis

Pregnancy-Related Cholestasis

Icp

Pregnancy Related Cholestasis

Cholestasis, Intrahepatic Of Pregnancy

Familial Intrahepatic Cholestasis Of Pregnancy

Familial Recurrent Intrahepatic Cholestasis Of Pregnancy

Ricp

Obstetric Cholestasis
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS13358 SLCO4A1 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS13359 SLCO4C1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Felis catus SLCO4A1 VGNC VGNC:65447
Bos taurus SLCO4A1 VGNC VGNC:34954
Rattus norvegicus SLCO4A1 RGD RGD:620228
Macaca mulatta SLCO4A1 VGNC VGNC:77599
Mus musculus SLCO4A1 MGD MGI:1351866
Canis familiaris SLCO4A1 VGNC VGNC:46498
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