1. Gene
  2. B4GALNT3 - beta-1,4-N-acetyl-galactosaminyltransferase 3 Gene

B4GALNT3 - beta-1,4-N-acetyl-galactosaminyltransferase 3 Gene

中文名称:β-1,4-N-乙酰半乳糖氨基转移酶 3

种属: Homo sapiens

基因 ID: 283358 | 基因类型: protein coding

关于 B4GALNT3

Cytogenetic location: 12p13.33 Genomic coordinates (GRCh38): 12:459,939-563,509 (from NCBI)

This gene has 7 transcripts (splice variants), 198 orthologues and 7 paralogues. Biased expression in stomach (RPKM 33.1), colon (RPKM 16.3) and 11 other tissues.

功能概要

B4GALNT3 将 N-乙酰半乳糖胺 (GalNAc) 转移到葡糖基残基上,形成 N,N-prime-二乙酰乳糖二胺 (LacdiNAc 或 LDN) ,这是细胞表面 N-聚糖的独特末端结构 (Ikehara 等人,2006 [PubMed 16728562]) 。[OMIM 提供,2008 年 8 月]

B4GALNT3 transfers N-acetylgalactosamine (GalNAc) onto glucosyl residues to form N,N-prime-diacetyllactosediamine (LacdiNAc, or LDN), a unique terminal structure of cell surface N-glycans (Ikehara et al., 2006 [PubMed 16728562]).[supplied by OMIM, Aug 2008]

B4GALNT3 基因产物(1)

mRNA Protein Name
NM_173593.4 NP_775864.3 beta-1,4-N-acetylgalactosaminyltransferase 3

B4GALNT3 蛋白结构

PA14

PA14: PA14 domain (130 - 275)

CHGN

CHGN: Chondroitin N-acetylgalactosaminyltransferase (672 - 983)

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  • 998 a.a.
蛋白主名 其他名称

beta-1,4-N-acetylgalactosaminyltransferase 3

B4GalNAcT3

关联疾病

疾病名称 别名
Idiopathic Peripheral Autonomic Neuropathy
Chronic Polyneuropathy
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus B4GALNT3 RGD RGD:1561056
Mus musculus B4GALNT3 MGD MGI:3041155
Macaca mulatta B4GALNT3 VGNC VGNC:70121
Felis catus B4GALNT3 VGNC VGNC:60064
Bos taurus B4GALNT3 VGNC VGNC:26387
Canis familiaris B4GALNT3 VGNC VGNC:38347