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  3. GPR20 - G protein-coupled receptor 20 Gene

GPR20 - G protein-coupled receptor 20 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：G 蛋白偶联受体 20

种属: Homo sapiens

基因 ID: 2843 | 基因类型: protein coding

关于 GPR20

Cytogenetic location: 8q24.3 Genomic coordinates (GRCh38): 8:141,356,470-141,367,286 (from NCBI)

This gene has 1 transcript (splice variant), 1 gene allele, 223 orthologues and 16 paralogues. Low expression observed in reference dataset.

功能概要

启用 G 蛋白偶联受体活性。预计参与磷脂酶 C 激活 G 蛋白偶联信号通路中 Rho 蛋白信号转导的正向调节和胞质钙离子浓度的正向调节。位于胞质溶胶和质膜中。是质膜的组成部分。受体复合体的一部分。 [由基因组资源联盟提供，2022 年 4 月]

Enables G protein-coupled receptor activity. Predicted to be involved in positive regulation of Rho protein signal transduction and positive regulation of cytosolic calcium ion concentration involved in Phospholipase C-activating G protein-coupled signaling pathway. Located in cytosol and plasma membrane. Is integral component of plasma membrane. Part of receptor complex. [provided by Alliance of Genome Resources, Apr 2022]

GPR20 基因产物(1)

mRNA Protein Name
NM_005293.3 NP_005284.2 G-protein coupled receptor 20

GPR20 蛋白结构

7tm_1

7tm_1: 7 transmembrane receptor (rhodopsin family) (71 - 297)

  • 0
  • 100
  • 200
  • 300
  • 358 a.a.
蛋白主名 其他名称

G-protein coupled receptor 20

CTD-3064M3.3

关联疾病

疾病名称 别名
Retinitis Pigmentosa 11

RP11

Retinitis Pigmentosa-11

Retinitis Pigmentosa, Type 11
Polycystic Kidney Disease 2 With Or Without Polycystic Liver Disease

Polycystic Kidney Disease 2

PKD2

Polycystic Kidney Disease, Adult, Type Ii

Apkd2

Polycystic Kidney Disease, Type 2

Adpkd2

Adult Polycystic Kidney Disease Type 2

Autosomal Dominant Polycystic Kidney Disease 2

Pkd-2

Polycystic Kidney Disease Adult Type Ii

Polycystic Kidney Type 2 Autosomal Dominant Disease

Kidney Disease, Polycystic, Type 2
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS05694 GPR20 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus GPR20 RGD RGD:620034
Felis catus GPR20 VGNC VGNC:67420
Bos taurus GPR20 VGNC VGNC:29579
Mus musculus GPR20 MGD MGI:2441803
Canis familiaris GPR20 VGNC VGNC:41425
Macaca mulatta GPR20 VGNC VGNC:104459
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