2. Gene
  3. NKIRAS2 - NFKB inhibitor interacting Ras like 2 Gene

NKIRAS2 - NFKB inhibitor interacting Ras like 2 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：NFKB 抑制因子相互作用 Ras 样 2

种属: Homo sapiens

同用名: KBRAS2; kappaB-Ras2

基因 ID: 28511 | 基因类型: protein coding

关于 NKIRAS2

Cytogenetic location: 17q21.2 Genomic coordinates (GRCh38): 17:42,017,576-42,025,641 (from NCBI)

This gene has 14 transcripts (splice variants), 204 orthologues and 35 paralogues. Ubiquitous expression in placenta (RPKM 30.4), esophagus (RPKM 22.7) and 25 other tissues.

功能概要

预计可启用 GTPase 激活蛋白结合活性。预计参与 I-kappaB 激酶/NF-kappaB 信号传导。预计在多个过程的上游或内部起作用，包括 Ral 蛋白信号转导；调节信号转导；和表面活性剂稳态。预计位于细胞质中。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable GTPase activating protein binding activity. Predicted to be involved in I-kappaB kinase/NF-kappaB signaling. Predicted to act upstream of or within several processes, including Ral protein signal transduction; regulation of signal transduction; and surfactant homeostasis. Predicted to be located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

NKIRAS2 基因产物(5)

mRNA Protein Name
NM_001001349.2 NP_001001349.1 NF-kappa-B inhibitor-interacting Ras-like protein 2 isoform a
NM_001144927.2 NP_001138399.1 NF-kappa-B inhibitor-interacting Ras-like protein 2 isoform a
NM_001144928.2 NP_001138400.1 NF-kappa-B inhibitor-interacting Ras-like protein 2 isoform b
NM_001144929.2 NP_001138401.1 NF-kappa-B inhibitor-interacting Ras-like protein 2 isoform c
NM_017595.6 NP_060065.2 NF-kappa-B inhibitor-interacting Ras-like protein 2 isoform a

NKIRAS2 蛋白结构

Ras

Ras: Ras family (6 - 169)

  • 0
  • 100
  • 191 a.a.
蛋白主名 其他名称

NF-kappa-B inhibitor-interacting Ras-like protein 2

I-kappa-B-interacting Ras-like protein 2

关联疾病

疾病名称 别名
Diffuse Lipomatosis
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS09321 NKIRAS2 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta NKIRAS2 VGNC VGNC:75205
Mus musculus NKIRAS2 MGD MGI:1919216
Rattus norvegicus NKIRAS2 RGD RGD:1307363
Bos taurus NKIRAS2 VGNC VGNC:32095
Canis familiaris NKIRAS2 VGNC VGNC:43830
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