1. Gene
  2. SCARA5 - scavenger receptor class A member 5 Gene

SCARA5 - scavenger receptor class A member 5 Gene

中文名称:清道夫受体 A 类成员 5

种属: Homo sapiens

同用名: Tesr; NET33

基因 ID: 286133 | 基因类型: protein coding

关于 SCARA5

Cytogenetic location: 8p21.1 Genomic coordinates (GRCh38): 8:27,869,883-27,992,673 (from NCBI)

This gene has 4 transcripts (splice variants), 188 orthologues and 3 paralogues. Broad expression in fat (RPKM 25.7), colon (RPKM 18.6) and 19 other tissues.

功能概要

预测可启用铁蛋白受体活性。预计参与多个过程,包括细胞铁离子稳态;铁离子跨膜转运;和蛋白质同源三聚化。预计在细胞对热的反应的上游或内部起作用。预测位于细胞表面。预计是质膜的组成部分。预计在质膜外侧活跃。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable ferritin receptor activity. Predicted to be involved in several processes, including cellular iron ion homeostasis; iron ion transmembrane transport; and protein homotrimerization. Predicted to act upstream of or within cellular response to heat. Predicted to be located in cell surface. Predicted to be integral component of plasma membrane. Predicted to be active in external side of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

SCARA5 基因产物(4)

mRNA Protein Name
NM_001413201.1 NP_001400130.1 scavenger receptor class A member 5 isoform 2
NM_001413202.1 NP_001400131.1 scavenger receptor class A member 5 isoform 3
NM_001413203.1 NP_001400132.1 scavenger receptor class A member 5 isoform 4
NM_173833.6 NP_776194.2 scavenger receptor class A member 5 isoform 1

SCARA5 蛋白结构

Collagen

Collagen: Collagen triple helix repeat (20 copies) (305 - 357)

Collagen

Collagen: Collagen triple helix repeat (20 copies) (327 - 379)

SRCR

SRCR: Scavenger receptor cysteine-rich domain (396 - 493)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 495 a.a.
蛋白主名 其他名称

scavenger receptor class A member 5

scavenger receptor class A, member 5 (putative)

关联疾病

疾病名称 别名
Prostate Leiomyosarcoma

Leiomyosarcoma Of The Prostate

Prostate Stromal Sarcoma

Stromal Sarcoma Of The Prostate

Facial Hemiatrophy

Parry-Romberg Syndrome

Hemochromatosis, Type 1

Hemochromatosis

Hemochromatosis Type 1

Hereditary Hemochromatosis

Hh

HFE1

Hfe Hemochromatosis, Modifier Of

Symptomatic Form Of Classic Hemochromatosis

Symptomatic Form Of Hemochromatosis Type 1

Symptomatic Form Of Hfe-Related Hereditary Hemochromatosis

Haemochromatosis

Iron Storage Disorder

Bronze Diabetes

Hereditary Haemochromatosis

Hlah

Hfe

Hemochromatosis, Hereditary

Diabetes Bronze

Classic Hemochromatosis

Hfe-Associated Hereditary Hemochromatosis

Hemochromatosis Classic

Bronzed Cirrhosis

Familial Hemochromatosis

Genetic Hemochromatosis

Hc

Pigmentary Cirrhosis

Primary Hemochromatosis

Troisier-Hanot-Chauffard Syndrome

Von Recklenhausen-Applebaum Disease

Hemochromatosis 1

Primary Hereditary Hemochromatosis

Bronze Cirrhosis

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Mus musculus SCARA5 MGD MGI:1918395
Macaca mulatta SCARA5 VGNC VGNC:77117
Bos taurus SCARA5 VGNC VGNC:34323
Canis familiaris SCARA5 VGNC VGNC:45897
Rattus norvegicus SCARA5 RGD RGD:1306539
Felis catus SCARA5 VGNC VGNC:64900