1. Gene
  2. Pbk - PDZ binding kinase Gene

Pbk - PDZ binding kinase Gene

中文名称:PDZ结合激酶

种属: Rattus norvegicus

基因 ID: 290326 | 基因类型: protein coding

关于 Pbk

Primary_assembly 15: 40,023,002-40,034,014 forward strand.mRatBN7.2:CM026988.1

This gene has 1 transcript (splice variant), 208 orthologues and is associated with 2 phenotypes. Biased expression in Testes (RPKM 96.), Thymus (RPKM 81.) and 8 other tissues.

功能概要

预测该基因编码的蛋白可启动蛋白质丝氨酸/苏氨酸激酶活性。预测参与蛋白质磷酸化。预计在几个过程的上游或内部起作用,包括细胞对紫外线的反应;细胞蛋白质代谢过程的负调节;和应激激活的 MAPK 级联的负调节。预测位于核内。与人 PBK(PDZ 结合激酶)同源。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in protein phosphorylation. Predicted to act upstream of or within several processes, including cellular response to UV; negative regulation of cellular protein metabolic process; and negative regulation of stress-activated MAPK cascade. Predicted to be located in nucleus. Orthologous to human PBK (PDZ binding kinase). [provided by Alliance of Genome Resources, Apr 2022]

Pbk 基因产物(1)

mRNA Protein Name
NM_001079937.1 NP_001073406.1 lymphokine-activated killer T-cell-originated protein kinase

Pbk 蛋白结构

PKc_TOPK

PKc_TOPK: cd14001 (31 - 318)

  • 0
  • 100
  • 200
  • 300
  • 337 a.a.
蛋白主名 其他名称

lymphokine-activated killer T-cell-originated protein kinase

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Pbk NCBI NCBI:55872