2. Gene
  3. CXCL3 - C-X-C motif chemokine ligand 3 Gene

CXCL3 - C-X-C motif chemokine ligand 3 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：CXC 基序趋化因子配体 3

种属: Homo sapiens

同用名: GRO3; GROg; MIP2B; SCYB3; MIP-2b; CINC-2b

基因 ID: 2921 | 基因类型: protein coding

关于 CXCL3

Cytogenetic location: 4q13.3 Genomic coordinates (GRCh38): 4:74,036,589-74,038,689 (from NCBI)

This gene has 4 transcripts (splice variants), 13 orthologues and 12 paralogues. Biased expression in appendix (RPKM 8.6), bone marrow (RPKM 6.3) and 12 other tissues.

功能概要

这种抗菌基因编码趋化因子 CXC 亚家族的一个成员。编码的蛋白质是一种分泌性生长因子，通过 G 蛋白偶联受体 CXC 受体 2 发出信号。该蛋白质在炎症中发挥作用，并作为嗜中性粒细胞的化学引诱物。[RefSeq 提供，2014 年 9 月]

This antimicrobial gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signals through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. [provided by RefSeq, Sep 2014]

CXCL3 基因产物(1)

mRNA Protein Name
NM_002090.3 NP_002081.2 C-X-C motif chemokine 3 precursor
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in antimicrobial humoral immune response mediated by antimicrobial peptide IDA
IDA: 通过直接分析推断
12949249 GOA
involved in killing of cells of another organism IDA
IDA: 通过直接分析推断
12949249 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
10095777 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

CXCL3 蛋白结构

IL8

IL8: Small cytokines (intecrine/chemokine), interleukin-8 like (40 - 99)

  • 0
  • 100
  • 107 a.a.
蛋白主名 其他名称

C-X-C motif chemokine 3

GRO-gamma

重组 CXCL3 蛋白

目录号 产品名 蛋白编号 纯度
HY-P7192 GRO-gamma/CXCL3 Protein, Human (CHO) P19876 (A35-N107) ≥95%
HY-P7193 GRO-gamma/CXCL3 Protein, Human P19876 (A35-N107) ≥95%
HY-P72678 GRO-gamma/CXCL3 Protein, Human (His) P19876 (A35-N107) ≥95%
HY-P72678AF Animal-Free GRO-gamma/CXCL3 Protein, Human (His) P19876 (A35-N107) ≥95%

关联疾病

疾病名称 别名
Melanoma

Malignant Melanoma

Cutaneous Melanoma

Naevocarcinoma

Malignant Melanomas
Colorectal Cancer

Colon Cancer

Colorectal Carcinoma

Colon Carcinoma

Colorectal Cancer, Susceptibility To

Carcinoma Of Colon

CRC

Colorectal Cancer With Chromosomal Instability, Somatic

Colon Cancer, Somatic

Colon Cancer, Susceptibility To

Colonic Neoplasms

Colorectal Neoplasms

Colorectal Cancer, Somatic

Colon Cancer, Advanced, Somatic

Colonic Carcinoma

Colorectal Carcinomas

Colon Cancers

Colorectal Cancers

Cancer, Colorectal, Somatic

Cancer, Colon

Cancer, Colorectal, Susceptibility To

Colorectal Neoplasm

Colonic Neoplasm

Malignant Tumor Of Colon
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS03392 CXCL3 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus CXCL3 NCBI NCBI:330122
Rattus norvegicus CXCL3 NCBI NCBI:171551
Others CXCL3 NCBI
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