1. Gene
  2. AURKC - aurora kinase C Gene

AURKC - aurora kinase C Gene

中文名称:极光激酶 C

种属: Rattus norvegicus

基因 ID: 292554 | 基因类型: protein coding

关于 AURKC

Primary_assembly 1: 66,843,653-66,864,386 reverse strand.mRatBN7.2:CM026974.1

This gene has 3 transcripts (splice variants), 99 orthologues, 2 paralogues and is associated with 4 phenotypes. Biased expression in Testes (RPKM 91.3), Brain (RPKM 4.2) and 9 other tissues.

功能概要

预测该基因编码的蛋白编码的蛋白可启动组蛋白丝氨酸激酶活性。预计参与有丝分裂纺锤体组织;蛋白质磷酸化;和胞质分裂的调节。预测作用于蛋白质自身磷酸化的上游或内部。预测位于染色体中;减数分裂纺锤体中区;和中体。预计是染色体乘客复合体的一部分。预计在纺锤体微管中有活性;主轴中间区;和纺锤体极中心体。该基因的人类直向同源物与生精失败 5 相关。与人类 AURKC(极光激酶 C)直向同源。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable histone serine kinase activity. Predicted to be involved in mitotic spindle organization; protein phosphorylation; and regulation of cytokinesis. Predicted to act upstream of or within protein autophosphorylation. Predicted to be located in chromosome; meiotic spindle midzone; and midbody. Predicted to be part of chromosome passenger complex. Predicted to be active in spindle microtubule; spindle midzone; and spindle pole centrosome. Human ortholog(s) of this gene implicated in spermatogenic failure 5. Orthologous to human AURKC (Aurora Kinase C). [provided by Alliance of Genome Resources, Apr 2022]

AURKC 基因产物(1)

mRNA Protein Name
NM_001308536.1 NP_001295465.1 aurora kinase C

AURKC 蛋白结构

PKc_like

PKc_like: cl21453 (55 - 324)

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  • 329 a.a.
蛋白主名 其他名称

aurora kinase C

serine/threonine-protein kinase 13

zinc finger protein 264-like

zinc finger protein 805-like

直系同源

种属 基因名 来源 基因 ID
Homo sapiens AURKC NCBI NCBI:6795