1. Gene
  2. Actc1 - actin, alpha, cardiac muscle 1 Gene

Actc1 - actin, alpha, cardiac muscle 1 Gene

种属: Rattus norvegicus

基因 ID: 29275 | 基因类型: protein coding

关于 Actc1

功能概要

Predicted to enable ATP binding activity; microfilament motor activity; and Myosin binding activity. Involved in cardiac muscle contraction; response to ethanol; and response to xenobiotic stimulus. Predicted to be located in several cellular components, including I band; filopodium; and lamellipodium. Predicted to be part of dynactin complex. Predicted to be active in actin filament; glutamatergic synapse; and sarcomere. Biomarker of hypertension. Human ortholog(s) of this gene implicated in atrial heart septal defect 5; dilated cardiomyopathy; dilated cardiomyopathy 1R; and hypertrophic cardiomyopathy 11. Orthologous to human ACTC1 (actin alpha cardiac muscle 1). [provided by Alliance of Genome Resources, Apr 2022]

Actc1 基因产物(1)

mRNA Protein Name
NM_019183.1 NP_062056.1 actin, alpha cardiac muscle 1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
12898519 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cardiac muscle contraction IDA
IDA: 通过直接分析推断
14551059 RGD
involved in response to ethanol IEP
IEP: 通过表达模式推断
15690316 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
16343576 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

actin, alpha cardiac muscle 1

actin, alpha, cardiac 1

alpha-actin cardiac

alpha-cardiac actin

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Actc1 NCBI NCBI:70