Pak1 - p21 (RAC1) activated kinase 1 Gene

中文名称：p21 (RAC1) 激活激酶 1

种属: Rattus norvegicus

关于 Pak1

功能概要

该基因编码的蛋白可启动蛋白激酶结合活性和蛋白丝氨酸/苏氨酸激酶活性。参与多个过程，包括参与心肌细胞发育的细胞生长的负调节；神经系统发育；和细胞迁移的正调控。位于多个细胞成分中，包括 Z 盘；闰盘;和荷叶边。脑缺血的生物标志物。该基因与乳腺癌相关的人类直向同源基因；肾细胞癌；和精神分裂症。与人 PAK1（p21 (RAC1) 激活激酶 1）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables protein kinase binding activity and protein serine/threonine kinase activity. Involved in several processes, including negative regulation of cell growth involved in cardiac muscle cell development; nervous system development; and positive regulation of cell migration. Located in several cellular components, including Z disc; intercalated disc; and ruffle. Biomarker of brain ischemia. Human ortholog(s) of this gene implicated in breast cancer; renal cell carcinoma; and schizophrenia. Orthologous to human PAK1 (p21 (RAC1) activated kinase 1). [provided by Alliance of Genome Resources, Apr 2022]