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  2. Mapk12 - mitogen-activated protein kinase 12 Gene

Mapk12 - mitogen-activated protein kinase 12 Gene

中文名称:丝裂原活化蛋白激酶 12

种属: Mus musculus

同用名: Erk6; Sapk3; Prkm12; P38gamma

基因 ID: 29857 | 基因类型: protein coding

关于 Mapk12

Chromosome 15: 89,014,787-89,024,906 reverse strand.GRCm39:CM001008.3

This gene has 7 transcripts (splice variants), 288 orthologues, 19 paralogues and is associated with 1 phenotype. Broad expression in cerebellum adult (RPKM 12.5), bladder adult (RPKM 9.4) and 25 other tissues.

功能概要

预测该基因编码的蛋白可启动 ATP 绑定活动; MAP 激酶活性;和镁离子结合活性。预计参与多个过程,包括细胞内信号转导;成肌细胞分化;和肽基丝氨酸磷酸化。预测作用于磷酸化上游或内部。预测位于核质中。预计在细胞质和细胞核中有活性。在帽间充质中表达;肺间充质;后肾;和嗅觉上皮。与人 MAPK12(丝裂原活化蛋白激酶 12)同源。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable ATP binding activity; MAP kinase activity; and magnesium ion binding activity. Predicted to be involved in several processes, including intracellular signal transduction; myoblast differentiation; and peptidyl-serine phosphorylation. Predicted to act upstream of or within phosphorylation. Predicted to be located in nucleoplasm. Predicted to be active in cytoplasm and nucleus. Is expressed in cap mesenchyme; lung mesenchyme; metanephros; and olfactory epithelium. Orthologous to human MAPK12 (mitogen-activated protein kinase 12). [provided by Alliance of Genome Resources, Apr 2022]

Mapk12 基因产物(5)

mRNA Protein Name
NM_001403020.1 NP_001389949.1 mitogen-activated protein kinase 12 isoform 3
NM_001403021.1 NP_001389950.1 mitogen-activated protein kinase 12 isoform 4
NM_013871.4 NP_038899.1 mitogen-activated protein kinase 12 isoform 1
NM_001403022.1 NP_001389951.1 mitogen-activated protein kinase 12 isoform 4
NM_001403019.1 NP_001389948.1 mitogen-activated protein kinase 12 isoform 2

Mapk12 蛋白结构

STKc_p38gamma

STKc_p38gamma: cd07880 (10 - 352)

  • 0
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  • 300
  • 367 a.a.
蛋白主名 其他名称

mitogen-activated protein kinase 12

ERK-6

MAP kinase 12

MAP kinase p38 gamma

MAPK 12

extracellular signal-regulated kinase 6

mitogen-activated protein kinase p38 gamma

stress-activated protein kinase 3

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Mapk12 NCBI NCBI:6300