1. Gene
  2. GNL2 - G protein nucleolar 2 Gene

GNL2 - G protein nucleolar 2 Gene

中文名称:G 蛋白核仁 2

种属: Homo sapiens

同用名: NGP1; Nog2; Nug2; Ngp-1; HUMAUANTIG

基因 ID: 29889 | 基因类型: protein coding

关于 GNL2

Cytogenetic location: 1p34.3 Genomic coordinates (GRCh38): 1:37,566,816-37,595,937 (from NCBI)

This gene has 9 transcripts (splice variants), 204 orthologues and 6 paralogues. Ubiquitous expression in testis (RPKM 19.5), bone marrow (RPKM 14.5) and 25 other tissues.

功能概要

启用 RNA 结合活性。预计参与核糖体生物合成。位于核仁。 [由基因组资源联盟提供,2022 年 4 月]

Enables RNA binding activity. Predicted to be involved in ribosome biogenesis. Located in nucleolus. [provided by Alliance of Genome Resources, Apr 2022]

GNL2 基因产物(3)

mRNA Protein Name
NM_001323623.2 NP_001310552.1 nucleolar GTP-binding protein 2 isoform 2
NM_001323624.2 NP_001310553.1 nucleolar GTP-binding protein 2 isoform 3
NM_013285.3 NP_037417.1 nucleolar GTP-binding protein 2 isoform 1

GNL2 蛋白结构

NGP1NT

NGP1NT: NGP1NT (NUC091) domain (43 - 174)

MMR_HSR1

MMR_HSR1: 50S ribosome-binding GTPase (313 - 379)

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  • 731 a.a.
蛋白主名 其他名称

nucleolar GTP-binding protein 2

autoantigen NGP-1

关联疾病

疾病名称 别名
Siberian Tick Typhus

North Asian Tick Typhus

Manchurian Typhus

North Asian Tick Fever

Rickettsia Sibirica Spotted Fever

Spotted Fever Group Rickettsiosis

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Bos taurus GNL2 VGNC VGNC:29472
Canis familiaris GNL2 VGNC VGNC:41326
Macaca mulatta GNL2 VGNC VGNC:73037
Felis catus GNL2 VGNC VGNC:62625
Rattus norvegicus GNL2 RGD RGD:1305006
Mus musculus GNL2 MGD MGI:2385207