2. Gene
  3. SLC2A8 - solute carrier family 2 member 8 Gene

SLC2A8 - solute carrier family 2 member 8 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：溶质载体家族 2 成员 8

种属: Homo sapiens

同用名: GLUT8; GLUTX1

基因 ID: 29988 | 基因类型: protein coding

关于 SLC2A8

Cytogenetic location: 9q33.3 Genomic coordinates (GRCh38): 9:127,397,169-127,407,898 (from NCBI)

This gene has 15 transcripts (splice variants), 261 orthologues and 13 paralogues. Broad expression in testis (RPKM 16.3), adrenal (RPKM 7.3) and 24 other tissues.

功能概要

该基因属于溶质载体 2A 家族，其中包括细胞内葡萄糖转运蛋白。基于序列比较，将葡萄糖转运蛋白分为三类，该基因属于 II 类。编码的蛋白质与该家族的其他成员一样，包含几个保守的残基和基序以及 12 个跨膜结构域，氨基和羧基末端均位于膜的胞质侧。已经描述了该基因的可变剪接转录物变体。[RefSeq 提供，2012 年 11 月]

This gene belongs to the solute carrier 2A family, which includes intracellular glucose transporters. Based on sequence comparison, the glucose transporters are grouped into three classes and this gene is a member of class II. The encoded protein, like Other members of the family, contains several conserved residues and motifs and 12 transmembrane domains with both amino and carboxyl ends being on the cytosolic side of the membrane. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Nov 2012]

SLC2A8 基因产物(3)

mRNA Protein Name
NM_001271711.2 NP_001258640.1 solute carrier family 2, facilitated glucose transporter member 8 isoform 2
NM_001271712.2 NP_001258641.1 solute carrier family 2, facilitated glucose transporter member 8 isoform 3
NM_014580.5 NP_055395.2 solute carrier family 2, facilitated glucose transporter member 8 isoform 1

SLC2A8 蛋白结构

Sugar_tr

Sugar_tr: Sugar (and other) transporter (30 - 473)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 477 a.a.
蛋白主名 其他名称

solute carrier family 2, facilitated glucose transporter member 8

glucose transporter type 8

关联疾病

疾病名称 别名
Type 1 Diabetes Mellitus 10

Diabetes Mellitus, Insulin-Dependent, 10

IDDM10

Insulin-Dependent Diabetes Mellitus 10

Diabetes, Mellitus, Insulin-Dependent, Susceptibility To, 10

T1D10

Diabetes, Mellitus, Insulin-Dependent 10

Diabetes Mellitus, Insulin-Dependent, Type 10
Arterial Tortuosity Syndrome

Arterial Tortuosity

Ats

ATORS

Tortuosity, Arterial, Syndrome
Hypoascorbemia

Scurvy

Ascorbic Acid Deficiency

Vitamin C Deficiency

Vitamin C, Inability To Synthesize

Deficiency Of Vitamin C

Scorbutus

Vitamin C
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-139047 SW157765 Inhibitor 98.08% 否
HY-RS13176 SLC2A8 Human Pre-designed siRNA Set A Pre-designed Sets / 否
抗体抑制剂 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P990674 VB1-050 Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus SLC2A8 VGNC VGNC:34803
Rattus norvegicus SLC2A8 RGD RGD:620611
Mus musculus SLC2A8 MGD MGI:1860103
Felis catus SLC2A8 VGNC VGNC:65306
Canis familiaris SLC2A8 VGNC VGNC:46344
Macaca mulatta SLC2A8 VGNC VGNC:77470
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