2. Gene
  3. LMCD1 - LIM and cysteine rich domains 1 Gene

LMCD1 - LIM and cysteine rich domains 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：LIM 和富半胱氨酸的结构域 1

种属: Homo sapiens

基因 ID: 29995 | 基因类型: protein coding

关于 LMCD1

Cytogenetic location: 3p25.3 Genomic coordinates (GRCh38): 3:8,501,823-8,574,668 (from NCBI)

This gene has 7 transcripts (splice variants), 202 orthologues and 3 paralogues. Broad expression in lung (RPKM 21.9), fat (RPKM 21.1) and 24 other tissues.

功能概要

该基因编码锌指蛋白 LIM 域家族的一个成员。编码的蛋白质包含一个 N 端富含半胱氨酸的结构域和两个 C 端 LIM 结构域。 LIM 结构域的存在表明参与了蛋白质-蛋白质相互作用。该蛋白质可以与其他转录因子一起作为转录的共同调节因子。交替剪接导致该基因的多个转录变体。[RefSeq 提供，2013 年 5 月]

This gene encodes a member of the LIM-domain family of zinc finger proteins. The encoded protein contains an N-terminal cysteine-rich domain and two C-terminal LIM domains. The presence of LIM domains suggests involvement in protein-protein interactions. The protein may act as a co-regulator of transcription along with other transcription factors. Alternate splicing results in multiple transcript variants of this gene. [provided by RefSeq, May 2013]

LMCD1 基因产物(4)

mRNA Protein Name
NM_001278233.2 NP_001265162.1 LIM and cysteine-rich domains protein 1 isoform 2
NM_001278234.2 NP_001265163.1 LIM and cysteine-rich domains protein 1 isoform 3
NM_001278235.2 NP_001265164.1 LIM and cysteine-rich domains protein 1 isoform 4
NM_014583.4 NP_055398.1 LIM and cysteine-rich domains protein 1 isoform 1

LMCD1 蛋白结构

PET

PET: PET Domain (98 - 202)

LIM

LIM: LIM domain (262 - 302)

LIM

LIM: LIM domain (308 - 360)

  • 0
  • 100
  • 200
  • 300
  • 365 a.a.
蛋白主名 其他名称

LIM and cysteine-rich domains protein 1

dyxin

重组 LMCD1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P70926 LMCD1 Protein, Human (His) Q9NZU5-1 (M1-S365) ≥95%

关联疾病

疾病名称 别名
Lidocaine Allergy

Lidoderm Allergy

Lignocaine Allergy

Xylocaine Allergy
Mixed Cell Uveal Melanoma

Intraocular Mixed Cell Type Melanoma

Mixed Cell Type Uveal Melanoma
Posterior Uveal Melanoma

Medium/Large Size Posterior Uveal Melanoma

Small Size Posterior Uveal Melanoma

Ciliary Body And Choroid Melanoma, Medium/Large Size

Ciliary Body And Choroid Melanoma, Small Size
Orthostatic Intolerance

Mitral Valve Prolapse

Neurocirculatory Asthenia

Mitral Valve Prolapse Syndrome

Irritable Heart

Systolic Click-Murmur Syndrome

Soldiers Heart

Cardiovascular Malfunction Arising From Mental Factors

Cardiovascular Neurosis

Da Costa'S Syndrome

Krishaber'S Disease

Barlow'S Syndrome

Floppy Mitral Valve

Mitral Leaflet Syndrome

Myxomatous Mitral Valve Prolapse

Postural Orthostatic Tachycardia Syndrome Due To Net Deficiency

Familial Orthostatic Tachycardia Due To Norepinephrine Transporter Deficiency

Orthostatic Intolerance Due To Net Deficiency

Pots Due To Net Deficiency

OI

Intolerance, Orthostatic

Mitral Valve Prolapse, Familial, X-Linked

Ballooning Mitral Valve

Barlow Syndrome

Flail Mitral Leaflet

Myxomatous Mitral Valve

Mitral Valve Prolapse-Click Syndrome

Prolapsing Mitral Valve Leaflet Syndrome

Billowing Mitral Valve Leaflet

Posterior Mitral Leaflet Deformity

Ballooning Posterior Leaflet Syndrome

Blue Valve Syndrome

Floppy Mitral Valve Syndrome

Mitral Valvular Prolapse

Systolic Click Syndrome
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS07710 LMCD1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Canis familiaris LMCD1 VGNC VGNC:42714
Bos taurus LMCD1 VGNC VGNC:30926
Felis catus LMCD1 VGNC VGNC:68065
Macaca mulatta LMCD1 VGNC VGNC:74426
Rattus norvegicus LMCD1 RGD RGD:1308963
Mus musculus LMCD1 MGD MGI:1353635
Others LMCD1 NCBI
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