Mmp1 - matrix metallopeptidase 1 Gene

中文名称：基质金属肽酶 1

种属: Rattus norvegicus

同用名: Clgn; MMP-1; Mmp1a

关于 Mmp1

功能概要

该基因编码的蛋白可启动肽酶活性。参与多个过程，包括细胞对细胞因子刺激的反应；女性性腺发育；和细胞迁移的正调控。位于细胞质和细胞外空间。用于研究多种疾病，包括动脉疾病（多种）；退行性椎间盘疾病；肝硬化;肺纤维化;和溃疡性结肠炎。多种疾病的生物标志物，包括慢性阻塞性肺病；肝硬化;脊柱侧弯;肌腱炎;和 2 型糖尿病。该基因的人类直系同源物与多种疾病有关，包括动脉疾病（多种）；女性生殖器官癌（多发性）；内在性心肌病（多发性）；阻塞性肺病（多发性）；和泌尿系统癌症（多发性）。与人 MMP1（基质金属肽酶 1）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables peptidase activity. Involved in several processes, including cellular response to cytokine stimulus; female gonad development; and positive regulation of cell migration. Located in cytoplasm and extracellular space. Used to study several diseases, including artery disease (multiple); degenerative disc disease; liver cirrhosis; pulmonary fibrosis; and ulcerative colitis. Biomarker of several diseases, including chronic obstructive pulmonary disease; liver cirrhosis; scoliosis; tendinitis; and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); female reproductive organ Cancer (multiple); intrinsic cardiomyopathy (multiple); obstructive lung disease (multiple); and urinary system Cancer (multiple). Orthologous to human MMP1 (matrix metallopeptidase 1). [provided by Alliance of Genome Resources, Apr 2022]