2. Gene
  3. Pde12 - phosphodiesterase 12 Gene

Pde12 - phosphodiesterase 12 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：磷酸二酯酶 12

种属: Rattus norvegicus

同用名: 2-PDE; 2'-PDE; LRRGT00074; RGD1310975

基因 ID: 306231 | 基因类型: protein coding

关于 Pde12

Primary_assembly 16: 1,915,386-1,925,887 reverse strand.mRatBN7.2:CM026989.1

This gene has 2 transcripts (splice variants), 204 orthologues, 5 paralogues and is associated with 2 phenotypes. Biased expression in Kidney (RPKM 17.6), Thymus (RPKM 84.7) and 9 other tissues.

功能概要

预测该基因编码的蛋白可启动 3'-5'-核糖核酸外切酶活性。预计参与多个过程，包括RNA代谢过程；对细胞因子刺激的细胞反应；和调节线粒体 mRNA 的稳定性。预测位于线粒体基质中。预测在线粒体中活跃。与人 PDE12（磷酸二酯酶 12）同源。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable 3'-5'-exoribonuclease activity. Predicted to be involved in several processes, including RNA metabolic process; cellular response to cytokine stimulus; and regulation of mitochondrial mRNA stability. Predicted to be located in mitochondrial matrix. Predicted to be active in mitochondrion. Orthologous to human PDE12 (phosphodiesterase 12). [provided by Alliance of Genome Resources, Apr 2022]

Pde12 基因产物(1)

mRNA Protein Name
NM_001411708.1 NP_001398637.1 2',5'-phosphodiesterase 12
蛋白主名 其他名称

2',5'-phosphodiesterase 12

mitochondrial deadenylase

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-124768 PDE12-IN-3 Inhibitor 98.02% 否
HY-117318 PDE12-IN-1 Inhibitor 98.85% 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Pde12 NCBI NCBI:201626
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