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  3. Pde6a - phosphodiesterase 6A Gene

Pde6a - phosphodiesterase 6A Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：磷酸二酯酶 6A

种属: Rattus norvegicus

基因 ID: 307401 | 基因类型: protein coding

关于 Pde6a

Primary_assembly 18: 54,676,863-54,748,816 forward strand.mRatBN7.2:CM026991.1

This gene has 1 transcript (splice variant), 100 orthologues, 20 paralogues and is associated with 8 phenotypes. Low expression observed in reference dataset.

功能概要

预计该基因编码的蛋白可实现 3',5'-环状核苷酸磷酸二酯酶活性。预计参与相机型眼的视网膜发育和信号转导。预计在光感受器细胞维护的上游或内部起作用。预测在光感受器外段膜中具有活性。该基因的人类直系同源物与色素性视网膜炎 43 相关。与人类 PDE6A（磷酸二酯酶 6A）直系同源。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable 3',5'-cyclic-nucleotide phosphodiesterase activity. Predicted to be involved in retina development in camera-type eye and signal transduction. Predicted to act upstream of or within photoreceptor cell maintenance. Predicted to be active in photoreceptor outer segment membrane. Human ortholog(s) of this gene implicated in retinitis pigmentosa 43. Orthologous to human PDE6A (phosphodiesterase 6A). [provided by Alliance of Genome Resources, Apr 2022]

Pde6a 基因产物(1)

mRNA Protein Name
NM_001107386.2 NP_001100856.1 rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha

Pde6a 蛋白结构

GAF

GAF: smart00065 (79 - 231)

GAF

GAF: smart00065 (253 - 440)

PDEase_I

PDEase_I: pfam00233 (557 - 801)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 860 a.a.
蛋白主名 其他名称

rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha

phosphodiesterase 6A, cGMP-specific, rod, alpha

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS10230 PDE6A Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS10231 Pde6a Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS10232 Pde6a Rat Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Pde6a NCBI NCBI:5145
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