2. Gene
  3. EHD4 - EH domain containing 4 Gene

EHD4 - EH domain containing 4 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：含 EH 结构域 4

种属: Homo sapiens

同用名: PAST4

基因 ID: 30844 | 基因类型: protein coding

关于 EHD4

Cytogenetic location: 15q15.1 Genomic coordinates (GRCh38): 15:41,895,933-41,972,557 (from NCBI)

This gene has 2 transcripts (splice variants), 205 orthologues and 10 paralogues. Ubiquitous expression in urinary bladder (RPKM 15.6), gall bladder (RPKM 14.3) and 25 other tissues.

功能概要

启用钙粘蛋白结合活动。参与内吞循环和蛋白质同源寡聚化。位于内质网和回收内体膜。 [由基因组资源联盟提供，2022 年 4 月]

Enables cadherin binding activity. Involved in endocytic recycling and protein homooligomerization. Located in endoplasmic reticulum and recycling endosome membrane. [provided by Alliance of Genome Resources, Apr 2022]

EHD4 基因产物(1)

mRNA Protein Name
NM_139265.4 NP_644670.1 EH domain-containing protein 4
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
17233914 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in endocytic recycling IGI
IGI: 通过遗传相互作用推断
17233914 GOA
involved in protein homooligomerization IPI
IPI: 通过物理相互作用推断
17233914 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in recycling endosome membrane IDA
IDA: 通过直接分析推断
17233914 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

EHD4 蛋白结构

Dynamin_N

Dynamin_N: Dynamin family (64 - 224)

EF-hand_4

EF-hand_4: Cytoskeletal-regulatory complex EF hand (450 - 534)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 541 a.a.
蛋白主名 其他名称

EH domain-containing protein 4

PAST homolog 4

关联疾病

疾病名称 别名
Ovarian Endometrial Cancer

Endometrioid Neoplasm Of Ovary

Malignant Ovarian Endometrioid Tumor

Ovarian Endometrioid Neoplasm
Cerebral Creatine Deficiency Syndrome 3

Arginine:Glycine Amidinotransferase Deficiency

Agat Deficiency

Gatm Deficiency

Creatine Deficiency Syndrome Due To Agat Deficiency

L-Arginine:Glycine Amidinotransferase Deficiency

CCDS3

L-Arginine:Glycine Aminidotransferase Deficiency

Deficiency, Cerebral Creatine, Syndrome, Type 3
Hepatocellular Carcinoma

Liver Cancer

Primary Liver Cancer

HCC

Hepatoma

Malignant Neoplasm Of Liver

Liver Neoplasms

Cancer, Hepatocellular

Liver Cell Carcinoma

Lcc

Hepatoblastoma, Somatic

Hepatic Cancer

Primary Malignant Neoplasm Of Liver

Rare Tumor Of Liver And Intrahepatic Biliary Tract

Hepatocellular Carcinoma, Somatic

Hepatocellular Carcinoma, Childhood Type, Somatic

Hepatocellular Cancer, Somatic

Ca Liver - Primary

Hepatic Neoplasm

Malignant Hepato-Biliary Neoplasm

Malignant Neoplasm Of Liver, Not Specified As Primary Or Secondary

Malignant Neoplasm Of Liver, Primary

Malignant Tumor Of Liver

Neoplasm Of Liver

Non-Resectable Primary Hepatic Malignant Neoplasm

Resectable Malignant Neoplasm Of Liver

Resectable Malignant Neoplasm Of The Liver

Primary Liver Carcinoma

Primary Malignant Liver Neoplasm

Primary Cancer Of Liver

Primary Tumor Of The Liver

Rare Tumor Of Liver And Ibt

Hepatocellular Cancer

Neoplasm Of The Liver

Carcinoma, Hepatocellular

Hepatomas

Liver Neoplasm

Liver Carcinoma

Liver And Intrahepatic Biliary Tract Carcinoma

Malignant Hepatobiliary Neoplasm

Adult Primary Hepatocellular Carcinoma

Hepatoblastoma

Carcinoma Of Liver

Malignant Liver Tumour

Malignant Hepatic Tumour
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-158415 ATPase-IN-4 / 否
HY-RS04224 EHD4 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS16299 Ehd4 Mouse Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus EHD4 VGNC VGNC:28374
Mus musculus EHD4 MGD MGI:1919619
Felis catus EHD4 VGNC VGNC:104385
Macaca mulatta EHD4 VGNC VGNC:72177
Rattus norvegicus EHD4 RGD RGD:628883
Canis familiaris EHD4 VGNC VGNC:40248
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