MAP3K7 - mitogen activated protein kinase kinase kinase 7 Gene

中文名称：有丝分裂原活化蛋白激酶激酶激酶 7

种属: Rattus norvegicus

同用名: Tak1

关于 MAP3K7

功能概要

该基因编码的蛋白可启动 ATP 结合活性和 MAP 激酶激酶活性。参与MAPK级联；细胞内信号转导的正向调节；和蛋白质磷酸化。预测位于胞质溶胶中；质膜;和突触后密度。该基因的人类直系同源物与额干骺端发育不良 2 和前列腺癌有关。与人 MAP3K7（丝裂原活化蛋白激酶激酶激酶 7）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables ATP binding activity and MAP kinase kinase kinase activity. Involved in MAPK cascade; positive regulation of intracellular signal transduction; and protein phosphorylation. Predicted to be located in cytosol; plasma membrane; and postsynaptic density. Human ortholog(s) of this gene implicated in frontometaphyseal dysplasia 2 and prostate Cancer. Orthologous to human MAP3K7 (mitogen-activated protein kinase kinase kinase 7). [provided by Alliance of Genome Resources, Apr 2022]