1. Gene
  2. Zhx2 - zinc fingers and homeoboxes 2 Gene

Zhx2 - zinc fingers and homeoboxes 2 Gene

中文名称:锌指和同源盒 2

种属: Rattus norvegicus

基因 ID: 314988 | 基因类型: protein coding

关于 Zhx2

Primary_assembly 7: 89,226,463-89,374,378 forward strand.mRatBN7.2:CM026980.1

This gene has 4 transcripts (splice variants), 237 orthologues, 3 paralogues and is associated with 2 phenotypes. Biased expression in Muscle (RPKM 82.), Kidney (RPKM 75.5) and 9 other tissues.

功能概要

预测该基因编码的蛋白编码的蛋白可启动 DNA 结合转录因子活性,RNA 聚合酶 II 特异性;蛋白质异二聚化活性;和蛋白质同二聚化活性。预测参与 RNA 聚合酶 II 和视网膜双极神经元分化对转录的负调节。预测作用于 mRNA 分解代谢过程的上游或内部;神经元分化的负调节;和成体干细胞群的维持。预计位于胞质溶胶和核质中。预计活跃于核心。与人类 ZHX2(锌指和同源框 2)同源。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific; protein heterodimerization activity; and protein homodimerization activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II and retinal bipolar neuron differentiation. Predicted to act upstream of or within mRNA catabolic process; negative regulation of neuron differentiation; and somatic stem cell population maintenance. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in nucleus. Orthologous to human ZHX2 (zinc fingers and homeoboxes 2). [provided by Alliance of Genome Resources, Apr 2022]

Zhx2 基因产物(1)

mRNA Protein Name
NM_001271056.1 NP_001257985.1 zinc fingers and homeoboxes protein 2

Zhx2 蛋白结构

zf_C2H2_ZHX

zf_C2H2_ZHX: pfam18387 (105 - 157)

homeodomain

homeodomain: cd00086 (271 - 320)

homeodomain

homeodomain: cd00086 (443 - 495)

HOX

HOX: smart00389 (536 - 581)

homeodomain

homeodomain: cd00086 (635 - 683)

  • 0
  • 200
  • 400
  • 600
  • 836 a.a.
蛋白主名 其他名称

zinc fingers and homeoboxes protein 2

AFP regulator 1

alpha-fetoprotein regulator 1

regulator of AFP

transcription factor ZHX2

zinc finger and homeodomain protein 2

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Zhx2 NCBI NCBI:22882