1. Gene
  2. Rps6ka6 - ribosomal protein S6 kinase A6 Gene

Rps6ka6 - ribosomal protein S6 kinase A6 Gene

中文名称:核糖体蛋白 S6 激酶 A6

种属: Rattus norvegicus

同用名: RGD1560817

基因 ID: 317203 | 基因类型: protein coding

关于 Rps6ka6

Primary_assembly X: 76,353,760-76,454,484 reverse strand.mRatBN7.2:CM026994.1

This gene has 4 transcripts (splice variants), 207 orthologues, 7 paralogues and is associated with 2 phenotypes. Biased expression in Brain (RPKM 29.), Kidney (RPKM 23.9) and 7 other tissues.

功能概要

预测该基因编码的蛋白编码的蛋白可启动核糖体蛋白 S6 激酶活性。预计参与多个过程,包括 DNA 损伤反应、p53 类介质的信号转导导致 p21 类介质的转录; ERK1ERK2 级联的负调控;和中胚层发育的负调控。预测位于纤维中心和线粒体。预计在细胞质和核质中有活性。与人 RPS6KA6(核糖体蛋白 S6 激酶 A6)同源。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable ribosomal protein S6 kinase activity. Predicted to be involved in several processes, including DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; negative regulation of ERK1 and ERK2 cascade; and negative regulation of mesoderm development. Predicted to be located in fibrillar center and mitochondrion. Predicted to be active in cytoplasm and nucleoplasm. Orthologous to human RPS6KA6 (ribosomal protein S6 kinase A6). [provided by Alliance of Genome Resources, Apr 2022]

Rps6ka6 基因产物(2)

mRNA Protein Name
NM_001191721.2 NP_001178650.1 ribosomal protein S6 kinase alpha-6
NM_001191721.2 NP_001178650.1 ribosomal protein S6 kinase alpha-6

Rps6ka6 蛋白结构

STKc_RSK_N

STKc_RSK_N: cd05582 (193 - 507)

STKc_RSK_C

STKc_RSK_C: cd14091 (542 - 828)

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  • 860 a.a.
蛋白主名 其他名称

ribosomal protein S6 kinase alpha-6

ribosomal protein S6 kinase polypeptide 6

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Rps6ka6 NCBI NCBI:27330