SLC29A2 - solute carrier family 29 member 2 Gene

中文名称：溶质载体家族 29 成员 2

种属: Homo sapiens

同用名: ENT2; DER12; HNP36

基因 ID: 3177 | 基因类型: protein coding

关于 SLC29A2

Cytogenetic location: 11q13.2 Genomic coordinates (GRCh38): 11:66,362,521-66,372,446 (from NCBI)

This gene has 7 transcripts (splice variants), 266 orthologues and 3 paralogues. Ubiquitous expression in duodenum (RPKM 6.4), small intestine (RPKM 4.5) and 23 other tissues.

功能概要

转运蛋白 (例如 SLC29A2) 对核苷的摄取对于在缺乏从头生物合成途径的细胞中通过补救途径合成核苷酸至关重要。核苷转运通过影响细胞表面的腺苷浓度，在许多生理过程的调节中也起着关键作用 (Griffiths 等人，1997 [PubMed 9396714]) 。[OMIM 提供，2008 年 11 月]

The uptake of nucleosides by transporters, such as SLC29A2, is essential for nucleotide synthesis by salvage pathways in cells that lack de novo biosynthetic pathways. Nucleoside transport also plays a key role in the regulation of many physiologic processes through its effect on adenosine concentration at the cell surface (Griffiths et al., 1997 [PubMed 9396714]).[supplied by OMIM, Nov 2008]

SLC29A2 基因产物(3)

mRNA	Protein	Name
NM_001300868.2	NP_001287797.1	equilibrative nucleoside transporter 2 isoform a
NM_001300869.2	NP_001287798.1	equilibrative nucleoside transporter 2 isoform b
NM_001532.3	NP_001523.2	equilibrative nucleoside transporter 2 isoform a

基因本体论

分子功能
生物过程
细胞组分

分子功能 GO 注释	逻辑证据	参考文献	来源
enables adenine transmembrane transporter activity	IDA IDA: 通过直接分析推断	21795683	GOA
enables cytidine transmembrane transporter activity	IDA IDA: 通过直接分析推断	10722669	GOA
enables guanine transmembrane transporter activity	IDA IDA: 通过直接分析推断	21795683	GOA
enables neurotransmitter transmembrane transporter activity	IDA IDA: 通过直接分析推断	9396714	GOA
enables nucleobase transmembrane transporter activity	IDA IDA: 通过直接分析推断	16214850	GOA
enables nucleoside transmembrane transporter activity	IDA IDA: 通过直接分析推断	9396714	GOA
enables purine nucleoside transmembrane transporter activity	IDA IDA: 通过直接分析推断	9396714	GOA
enables uracil transmembrane transporter activity	IDA IDA: 通过直接分析推断	21795683	GOA
enables uridine transmembrane transporter activity	IDA IDA: 通过直接分析推断	9396714	GOA

生物过程 GO 注释	逻辑证据	参考文献	来源
involved in adenine transport	IDA IDA: 通过直接分析推断	21795683	GOA
involved in adenosine transport	IDA IDA: 通过直接分析推断	9396714	GOA
involved in cytidine transport	IDA IDA: 通过直接分析推断	10722669	GOA
involved in guanine transmembrane transport	IDA IDA: 通过直接分析推断	21795683	GOA
involved in hypoxanthine transport	IDA IDA: 通过直接分析推断	16214850	GOA
involved in inosine transport	IDA IDA: 通过直接分析推断	10722669	GOA
involved in neurotransmitter transport	IDA IDA: 通过直接分析推断	9396714	GOA
involved in nucleobase transport	IDA IDA: 通过直接分析推断	16214850	GOA
involved in nucleoside transmembrane transport	IDA IDA: 通过直接分析推断	9396714	GOA
involved in nucleoside transport	IDA IDA: 通过直接分析推断	9396714	GOA
involved in purine nucleobase transmembrane transport	IDA IDA: 通过直接分析推断	16214850	GOA
involved in purine nucleoside transmembrane transport	IDA IDA: 通过直接分析推断	9396714	GOA
involved in pyrimidine-containing compound transmembrane transport	IDA IDA: 通过直接分析推断	9396714	GOA
involved in thymine transport	IDA IDA: 通过直接分析推断	21795683	GOA
involved in uracil transmembrane transport	IDA IDA: 通过直接分析推断	21795683	GOA
involved in uridine transmembrane transport	IDA IDA: 通过直接分析推断	9396714	GOA

细胞组分 GO 注释	逻辑证据	参考文献	来源
located in apical plasma membrane	IDA IDA: 通过直接分析推断	23639800	GOA
located in basolateral plasma membrane	IDA IDA: 通过直接分析推断	12527552	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

SLC29A2 蛋白结构

Nucleoside_tran

0
100
200
300
400
456 a.a.

蛋白主名

其他名称

equilibrative nucleoside transporter 2

36 kDa nucleolar protein HNP36

SLC29A2 抗体

目录号	产品名	应用	反应物种
HY-P82697	ENT2 Antibody (YA2442)	WB, ICC/IF, FC	Human, Mouse, Rat

关联疾病

疾病名称

别名

Hepatic Adenomas, Familial

Hepatic Adenoma, Somatic	Familial Hepatic Adenoma
Familial Liver Cell Adenomas	Liver Cell Adenomas, Familial
Hepatic Adenomas Familial	HEPAF
Ha	Hepatocellular Adenomas
Hepatocellular Adenoma

Leukemia, Chronic Lymphocytic

Chronic Lymphocytic Leukemia	B-Cell Chronic Lymphocytic Leukemia
CLL	B-Cell Chronic Lymphoid Leukemia
Chronic Lymphatic Leukemia	Chronic Lymphocytic Leukaemia
Lymphoplasmacytic Leukemia	Small Lymphocytic Lymphoma
Leukemia, Chronic Lymphatic	B-Cell Chronic Lymphocytic Leukaemia
Chronic Lymphatic Leukaemia	Lymphoplasmacytic Leukaemia
B Cell Chronic Lymphocytic Leukemia	Chronic B-Cell Lymphocytic Leukemia
Leukemia, Lymphocytic, Chronic	B-Cll
Chronic Lymphoid Leukemia	Leukemia Lymphocytic Chronic
Lymphoma Small Lymphocytic	Leukemia, Lymphocytic, Chronic, B-Cell

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS13154	SLC29A2 Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Felis catus	SLC29A2	VGNC	VGNC:65296
Macaca mulatta	SLC29A2	VGNC	VGNC:77446
Rattus norvegicus	SLC29A2	RGD	RGD:69296
Bos taurus	SLC29A2	VGNC	VGNC:34794
Canis familiaris	SLC29A2	VGNC	VGNC:46334
Mus musculus	SLC29A2	MGD	MGI:1345278
Others	SLC29A2	NCBI

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

SLC29A2 - solute carrier family 29 member 2 Gene

关于 SLC29A2

功能概要

SLC29A2 基因产物(3)

SLC29A2 蛋白结构

SLC29A2 抗体

关联疾病

直系同源

热门区域

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SLC29A2 - solute carrier family 29 member 2 Gene

关于 SLC29A2

功能概要

SLC29A2 基因产物(3)

SLC29A2 蛋白结构

SLC29A2 抗体

关联疾病

相关产品

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z