2. Gene
  3. HOXA6 - homeobox A6 Gene

HOXA6 - homeobox A6 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：同源框 A6

种属: Homo sapiens

同用名: HOX1; HOX1B; HOX1.2

基因 ID: 3203 | 基因类型: protein coding

关于 HOXA6

Cytogenetic location: 7p15.2 Genomic coordinates (GRCh38): 7:27,145,396-27,147,774 (from NCBI)

This gene has 2 transcripts (splice variants), 118 orthologues and 42 paralogues. Biased expression in endometrium (RPKM 5.2), kidney (RPKM 2.8) and 10 other tissues.

功能概要

在脊椎动物中，编码称为同源盒基因的转录因子类的基因位于四个独立染色体上名为 A、B、C 和 D 的簇中。这些蛋白质的表达在胚胎发育过程中受到时空调控。该基因是 7 号染色体 A 簇的一部分，编码 DNA 结合转录因子，可调节基因表达、形态发生和分化。[RefSeq 提供，2008 年 7 月]

In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. [provided by RefSeq, Jul 2008]

HOXA6 基因产物(1)

mRNA Protein Name
NM_024014.4 NP_076919.1 homeobox protein Hox-A6
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables sequence-specific double-stranded DNA binding IDA
IDA: 通过直接分析推断
28473536 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

HOXA6 蛋白结构

Homeobox

Homeobox: Homeobox domain (156 - 212)

  • 0
  • 100
  • 200
  • 233 a.a.
蛋白主名 其他名称

homeobox protein Hox-A6

homeo box 1B

关联疾病

疾病名称 别名
Angiomatous Meningioma
Parasagittal Meningioma
Cerebral Convexity Meningioma

Cerebral Hemispheric Convexity Meningioma
Foster-Kennedy Syndrome

Disorder Of The Optic Nerve

Optic Nerve Diseases

Disease Of Optic Cranial Nerve

Disease Of Optic Nerve

Disease Of Second Cranial Nerve

Disorder Of Optic Cranial Nerve

Disorder Of Second Cranial Nerve

Disorders Of 2nd Nerve
Clear Cell Meningioma
Anterior Cranial Fossa Meningioma

Meningioma Of The Anterior Fossa
Cerebral Falx Meningioma

Falcine Meningioma

Falx Cerebri Meningioma
Choroid Plexus Meningioma

Choroid Meningioma

Meningioma Of The Choroid Plexus
Brain Meningioma

Intracranial Meningioma
Cerebral Meningioma

Meningioma Of Cerebrum
Meningioma, Familial

Meningioma

Familial Meningioma

Meningioma, Familial, Susceptibility To

Meningeal Neoplasm

Meningeal Neoplasms

Meningiomas

Meningioma, Nf2-Related, Somatic

Meningioma, Sis-Related

Meningothelial Cell Tumor

Neoplasm Of The Meninges

Primary Meningeal Tumor

Familial Multiple Meningioma

MNGMA

Meningioma, Benign, No Icd-O Subtype

Intracranial Meningioma

Meningothelial Cell Neoplasm

Supratentorial Meningioma

Primary Neoplasm Of Spinal Meninges

Benign Intracranial Meningioma

Benign Meningioma

Meningeal Tumours

Meningeal Sarcoma Of Unspecified Site

Meningothelial Sarcoma Of Unspecified Site
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS06301 HOXA6 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus HOXA6 RGD RGD:1590236
Canis familiaris HOXA6 VGNC VGNC:49909
Mus musculus HOXA6 MGD MGI:96178
Macaca mulatta HOXA6 VGNC VGNC:108415
Bos taurus HOXA6 VGNC VGNC:29914
Felis catus HOXA6 VGNC VGNC:80598
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