2. Gene
  3. HTR1F - 5-hydroxytryptamine receptor 1F Gene

HTR1F - 5-hydroxytryptamine receptor 1F Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：5-羟色胺受体 1F

种属: Homo sapiens

同用名: 5HT6; MR77; 5-HT1F; HTR1EL; 5-HT-1F

基因 ID: 3355 | 基因类型: protein coding

关于 HTR1F

Cytogenetic location: 3p11.2-p11.1 Genomic coordinates (GRCh38): 3:87,792,706-87,993,839 (from NCBI)

This gene has 1 transcript (splice variant), 147 orthologues and 8 paralogues. Low expression observed in reference dataset.

功能概要

启用 G 蛋白偶联血清素受体活性和血清素结合活性。参与腺苷酸环化酶抑制 G 蛋白偶联受体信号通路。是质膜的组成部分。 [由基因组资源联盟提供，2022 年 4 月]

Enables G protein-coupled serotonin receptor activity and serotonin binding activity. Involved in adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway. Is integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

HTR1F 基因产物(4)

mRNA Protein Name
NM_000866.5 NP_000857.1 5-hydroxytryptamine receptor 1F
NM_001322208.2 NP_001309137.1 5-hydroxytryptamine receptor 1F
NM_001322209.2 NP_001309138.1 5-hydroxytryptamine receptor 1F
NM_001322210.2 NP_001309139.1 5-hydroxytryptamine receptor 1F
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables G protein-coupled serotonin receptor activity IDA
IDA: 通过直接分析推断
8380639 GOA
enables G protein-coupled serotonin receptor activity IMP
IMP: 通过突变表型推断
21422162 GOA
enables Gi/o-coupled serotonin receptor activity IDA
IDA: 通过直接分析推断
34239069 GOA
enables serotonin binding IDA
IDA: 通过直接分析推断
8380639 GOA
enables serotonin receptor activity IDA
IDA: 通过直接分析推断
34239069 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway IMP
IMP: 通过突变表型推断
21422162 GOA
involved in adenylate cyclase-inhibiting serotonin receptor signaling pathway IDA
IDA: 通过直接分析推断
34239069 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in plasma membrane IMP
IMP: 通过突变表型推断
21422162 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

HTR1F 蛋白结构

7tm_1

7tm_1: 7 transmembrane receptor (rhodopsin family) (41 - 347)

  • 0
  • 100
  • 200
  • 300
  • 366 a.a.
蛋白主名 其他名称

5-hydroxytryptamine receptor 1F

5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled

关联疾病

疾病名称 别名
Migraine With Or Without Aura 1

Migraine

Migraine With Or Without Aura, Susceptibility To, 1

Migraine Disorder

Migraine Variant

Migraines

Migraine Disorders

Mgr1

Mgau

Ma

Migraine With Or Without Aura

Classic Migraine

Common Migraine

Disorder, Migraine

Headache Migraine

Headache Migrainous

Migraine Headache

Migraine Syndrome

Headache Including Migraine

Migraine, Susceptibility To
Intracranial Vasospasm

Vasospasm, Intracranial
Tolosa-Hunt Syndrome

Painful Ophthalmoplegia

Tolosa Hunt Syndrome

Nonspecific Inflammation Of The Cavernous Sinus Or Superior Orbital Fissure

Ths

Ophthalmoplegia, Painful
Dyslexia
Migraine With Aura

Classic Migraine

Migraine With Typical Aura

Migraine Accompagnée

Complicated Migraine

Classical Migraine

Acute Migraine With Aura
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS06464 HTR1F Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus HTR1F RGD RGD:71083
Canis familiaris HTR1F VGNC VGNC:41826
Bos taurus HTR1F VGNC VGNC:29995
Felis catus HTR1F VGNC VGNC:67671
Mus musculus HTR1F MGD MGI:99842
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