CLEC4D - C-type lectin domain family 4 member D Gene

中文名称：C 型凝集素结构域家族 4 成员 D

种属: Homo sapiens

同用名: MCL; MPCL; CD368; CLEC6; CLEC-6; CLECSF8; Dectin-3

基因 ID: 338339 | 基因类型: protein coding

关于 CLEC4D

Cytogenetic location: 12p13.31 Genomic coordinates (GRCh38): 12:8,513,503-8,531,696 (from NCBI)

This gene has 2 transcripts (splice variants), 770 orthologues and 14 paralogues. Biased expression in bone marrow (RPKM 17.6), appendix (RPKM 4.0) and 1 other tissue.

功能概要

该基因编码 C 型凝集素/C 型凝集素样结构域 (CTL/CTLD) 超家族的成员。该家族的成员具有共同的蛋白质折叠并具有多种功能，例如细胞粘附、细胞间信号传导、糖蛋白转换以及在炎症和免疫反应中的作用。该基因与自然杀伤基因复合区 12p13 染色体上的其他 CTL/CTLD 超家族成员密切相关。[RefSeq 提供，2008 年 7 月]

This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. This gene is closely linked to Other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region. [provided by RefSeq, Jul 2008]

CLEC4D 基因产物(1)

mRNA	Protein	Name
NM_080387.5	NP_525126.2	C-type lectin domain family 4 member D

基因本体论

分子功能
生物过程
细胞组分

分子功能 GO 注释	逻辑证据	参考文献	来源
enables D-mannose binding	IDA IDA: 通过直接分析推断	23911656	GOA
enables pattern recognition receptor activity	IDA IDA: 通过直接分析推断	23911656	GOA
enables protein binding	IPI IPI: 通过物理相互作用推断	23911656	GOA

生物过程 GO 注释	逻辑证据	参考文献	来源
involved in antifungal innate immune response	IDA IDA: 通过直接分析推断	23911656	GOA

细胞组分 GO 注释	逻辑证据	参考文献	来源
is active in plasma membrane	IDA IDA: 通过直接分析推断	23911656	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

CLEC4D 蛋白结构

Lectin_C

0
100
200
215 a.a.

蛋白主名

其他名称

C-type lectin domain family 4 member D

C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 8

重组 CLEC4D 蛋白

目录号	产品名	蛋白编号	纯度
HY-P76834	CLEC4D Protein, Human (HEK293, His)	Q8WXI8 (G52-N215)	≥95%

关联疾病

疾病名称

别名

Subcutaneous Mycosis

Subcutaneous Fungal Disease

Phaeohyphomycosis

Infection By Dematiacious Fungi	Phaehyphomycosis
Phaeomycosis	Pheohyphomycosis
Infection By Dematiacious Fungi [Phaehyphomycosis]	Dematiaceous Fungal Infection

Blastomycosis

Gilchrist'S Disease	North American Blastomycosis
Blastomyces Dermatitidis Infection	Blastomycotic Infection
Infection By Blastomyces Dermatitidis	Gilchrist Disease
Chicago Disease	Chicago Disease Or Disorder
Blastomycosis, Unspecified	Blastomyces Infection

Chromoblastomycosis

Chromomycosis	Mossy Foot Disease
Verrucous Dermatitis	Fonseca Disease
Pedroso Disease	Drechslera Hawaiiensis
Drechslera Infection

Vulvovaginal Candidiasis

Candidiasis Of Vulva And Vagina	Candidiasis, Vulvovaginal
Candidal Vulvovaginitis	Candidal: Cervix
Monilial Vulvovaginitis	Candidiasis Vulvovaginal

Dermatophytosis

Tinea	Dermatophytosis, Unspecified
Ringworm	Infections Due To Species Of Epidermophyton, Microsporum And Trichophyton
Cutaneous Mycosis	Dermal Mycosis
Superficial Mycosis, Unspecified	Fungus Infection Of Skin
Skin Mycosis	Dermatitis Fungoid
Fungal Dermatitis	Fungal Dermatosis
Mycotic Infection Of Skin

Tinea Corporis

Dermatophytosis Of The Body

Dermatophytosis Of The Trunk

Cryptococcosis

Cryptococcus Neoformans Infection	Torulosis
Busse-Buschke'S Disease	Cryptococcal Infection
European Cryptococcosis	Torula
Infection By Cryptococcus Neoformans	Cryptococcosis Infection
European Blastomycosis	European Blastomycotic Infection
European Blastomycoses Infection	Torula Histolytica Infection

Primary Systemic Mycosis

Opportunistic Mycosis

Opportunistic Mycoses

Opportunistic Systemic Mycoses

Fungal Infectious Disease

Mycoses

Mycosis

Chronic Mucocutaneous Candidiasis

Candidiasis, Chronic Mucocutaneous	Cmc
Candidiasis Chronic Mucocutaneous

Immune Deficiency Disease

Immunodeficiency	Primary Immunodeficiency
Primary Immunodeficiency Disease	Immunologic Deficiency Syndromes
Hypoimmunity	Immune Deficiency Disorder
Immunodeficiency Syndrome	Immune Disorder
Primary Immune Deficiency Disorder	Immune System Diseases
Human Immunodeficiency Virus Infection	Hiv - [Human Immunodeficiency Virus Infection]
Hiv Positive Nos	Hiv Disease
Acquired Immune Deficiency Syndrome-Related Complex	Aids-Like Syndrome
Aids-Related Complex Nos	Arc - [Aids-Related Complex]
Immunodeficiency Due To Human Immunodeficiency Virus Infection	Unspecified Human Immunodeficiency Virus Disease
Hiv Disease Nos	Human Immunodeficiency Virus Positive Nos
Hiv Nos	Deficiency Of Complement Initial Pathway
Deficiency Of Complement Terminal Pathway	Cfdd - [Complement Factor D Deficiency]
Immunodeficiency With Nk-Cell - [Natural-Killer Cell] Deficiency	Nonfamilial Hypogammaglobulinaemia
Common Variable Immune Deficiency	Nonfamilial Agammaglobulinaemia
Common Variable Agammaglobulinaemia	Agammaglobulinaemia Nos
Agammaglobulinaemia Antibody Deficiency Syndrome	Hypogammaglobulinaemia Antibody Deficiency Syndrome
Acquired Agammaglobulinaemia Nos	Hypogammaglobulinaemia Nos
Hyper Igm

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS02793	CLEC4D Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Felis catus	CLEC4D	VGNC	VGNC:60951
Macaca mulatta	CLEC4D	VGNC	VGNC:71178
Bos taurus	CLEC4D	VGNC	VGNC:27431
Mus musculus	CLEC4D	MGD	MGI:1298389
Rattus norvegicus	CLEC4D	RGD	RGD:1303339
Others	CLEC4D	NCBI

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

CLEC4D - C-type lectin domain family 4 member D Gene

关于 CLEC4D

功能概要

CLEC4D 基因产物(1)

CLEC4D 蛋白结构

重组 CLEC4D 蛋白

关联疾病

直系同源

热门区域

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CLEC4D - C-type lectin domain family 4 member D Gene

关于 CLEC4D

功能概要

CLEC4D 基因产物(1)

CLEC4D 蛋白结构

重组 CLEC4D 蛋白

关联疾病

相关产品

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z