2. Gene
  3. ZC3H12D - zinc finger CCCH-type containing 12D Gene

ZC3H12D - zinc finger CCCH-type containing 12D Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：含 12D 锌指 CCCH 型

种属: Homo sapiens

同用名: TFL; p34; MCPIP4; C6orf95; dJ281H8.1

基因 ID: 340152 | 基因类型: protein coding

关于 ZC3H12D

Cytogenetic location: 6q25.1 Genomic coordinates (GRCh38): 6:149,446,795-149,485,014 (from NCBI)

This gene has 5 transcripts (splice variants), 128 orthologues and 6 paralogues. Biased expression in lymph node (RPKM 4.6), appendix (RPKM 3.5) and 11 other tissues.

功能概要

预测启用核糖核酸内切酶活性和 mRNA 结合活性。参与有丝分裂细胞周期 G1/S 转换的负调节和细胞生长的负调节。位于 P 体和核质中。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable endoribonuclease activity and mRNA binding activity. Involved in negative regulation of G1/S transition of mitotic cell cycle and negative regulation of cell growth. Located in P-body and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

ZC3H12D 基因产物(1)

mRNA Protein Name
NM_207360.3 NP_997243.2 probable ribonuclease ZC3H12D
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
26134560 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of G1/S transition of mitotic cell cycle IDA
IDA: 通过直接分析推断
19531561 GOA
involved in negative regulation of cell growth IDA
IDA: 通过直接分析推断
19531561 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in P-body IDA
IDA: 通过直接分析推断
24415781 GOA
located in cytoplasm IDA
IDA: 通过直接分析推断
19531561 GOA
located in nucleus IDA
IDA: 通过直接分析推断
19531561 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

ZC3H12D 蛋白结构

RNase_Zc3h12a

RNase_Zc3h12a: Zc3h12a-like Ribonuclease NYN domain (89 - 243)

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  • 527 a.a.
蛋白主名 其他名称

probable ribonuclease ZC3H12D

Zinc finger CCCH domain-containing protein 12D

关联疾病

疾病名称 别名
Follicular Lymphoma

Lymphoma, Follicular

Lymphoma Follicular

Brill-Symmers' Disease

Large Cell Follicular Non-Hodgkin Lymphoma

Diffuse Follicle Centre Lymphoma

Diffuse Follicular Lymphoma Nos

Follicular Nodular Non-Hodgkin Lymphoma, Unspecified

Follicular Large Cell Cleaved Or Noncleaved Lymphoma

Large Cell Follicular Noncleaved Lymphoma

Follicular Lymphoma With Or Without Diffuse Areas

Histiocytic Follicular Lymphoma

Histiocytic Nodular Lymphoma

Histiocytic Nodular Malignant Lymphoma

Large Cell Follicular Lymphoma

Large Cell Noncleaved Follicular Lymphoma

Large Cell Noncleaved Follicular Malignant Lymphoma

Nodular Reticulum Cell Sarcoma

Noncleaved Follicular Lymphoma
Lymphoma

Lymphoid Cancer

Lymphomas

Lymphoid Cancers

Lymphoid Neoplasm

Lymphoma Nos

Nhl - [Non-Hodgkin Lymphoma]

Non-Hodgkin Lymphoma

Non-Hodgkin Lymphoma, Nos

Non-Hodgkin Malignant Lymphoma Nos
Diffuse Large B-Cell Lymphoma

Dlbcl

Diffuse Large B-Cell Lymphoma, Not Otherwise Specified

Large B-Cell Diffuse Lymphoma

Lymphoma, Large B-Cell, Diffuse

Dlbcl - [Diffuse Large B-Cell Lymphoma]

Diffuse Large Beta Cell Lymphoma
Eastern Equine Encephalitis

Eee

Neuroinvasive Eastern Equine Encephalitis Virus Infection

Eastern Equine Encephalomyelitis

Encephalomyelitis, Eastern Equine

Triple E

Eastern Equine Encephalitis Virus Infection

Neuroinvasive Eastern Equine Encephalitis Virus Disease

Eee - [Eastern Equine Encephalitis]
Drug-Induced Lupus Erythematosus

Dile

Dil

Drug-Induced Systemic Lupus Erythematosus
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS15987 ZC3H12D Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Felis catus ZC3H12D VGNC VGNC:102555
Bos taurus ZC3H12D VGNC VGNC:37100
Canis familiaris ZC3H12D VGNC VGNC:54006
Macaca mulatta ZC3H12D VGNC VGNC:83972
Mus musculus ZC3H12D MGD MGI:3045313
Rattus norvegicus ZC3H12D RGD RGD:1597152
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