2. Gene
  3. NEK5 - NIMA related kinase 5 Gene

NEK5 - NIMA related kinase 5 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：NIMA 相关激酶 5

种属: Homo sapiens

基因 ID: 341676 | 基因类型: protein coding

关于 NEK5

Cytogenetic location: 13q14.3 Genomic coordinates (GRCh38): 13:52,033,611-52,129,073 (from NCBI)

This gene has 8 transcripts (splice variants), 186 orthologues and 8 paralogues. Biased expression in testis (RPKM 3.0), lung (RPKM 0.4) and 1 other tissue.

功能概要

预测启用 ATP 绑定活动；金属离子结合活性；和蛋白激酶活性。预测参与蛋白质磷酸化。预计在半胱氨酸型内肽酶活性的正调节和横纹肌细胞分化的正调节的上游或内部起作用。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable ATP binding activity; metal ion binding activity; and protein kinase activity. Predicted to be involved in protein phosphorylation. Predicted to act upstream of or within positive regulation of cysteine-type endopeptidase activity and positive regulation of striated muscle cell differentiation. [provided by Alliance of Genome Resources, Apr 2022]

NEK5 基因产物(2)

mRNA Protein Name
NM_001365552.1 NP_001352481.1 serine/threonine-protein kinase Nek5 isoform 2
NM_199289.3 NP_954983.1 serine/threonine-protein kinase Nek5 isoform 1

NEK5 蛋白结构

Pkinase

Pkinase: Protein kinase domain (4 - 259)

  • 0
  • 200
  • 400
  • 600
  • 708 a.a.
蛋白主名 其他名称

serine/threonine-protein kinase Nek5

NIMA (never in mitosis gene a)-related kinase 5

关联疾病

疾病名称 别名
Bardet-Biedl Syndrome 1

BBS1

Bardet-Biedl Syndrome 1, Modifier Of

Bardet-Biedl Syndrome

BBS

Bardet-Biedl Syndrome, Type 1

Laurence-Moon-Bardet-Biedl Syndrome
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS09196 NEK5 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Felis catus NEK5 VGNC VGNC:68458
Macaca mulatta NEK5 VGNC VGNC:75310
Rattus norvegicus NEK5 RGD RGD:1593817
Bos taurus NEK5 VGNC VGNC:31996
Mus musculus NEK5 MGD MGI:2142824
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