1. Gene
  2. GNAT3 - G protein subunit alpha transducin 3 Gene

GNAT3 - G protein subunit alpha transducin 3 Gene

中文名称:G 蛋白亚基α转导蛋白 3

种属: Homo sapiens

同用名: GDCA; HG1E

基因 ID: 346562 | 基因类型: protein coding

关于 GNAT3

Cytogenetic location: 7q21.11 Genomic coordinates (GRCh38): 7:80,458,635-80,512,064 (from NCBI)

This gene has 1 transcript (splice variant), 238 orthologues and 15 paralogues. Low expression observed in reference dataset.

功能概要

甜味、苦味和鲜味是通过特定的鸟嘌呤核苷酸结合蛋白从味觉受体传递而来的。该基因编码的蛋白质是这种异源三聚体 G 蛋白的 α 亚基,它不仅存在于口腔上皮细胞中,也存在于肠道组织中。该基因的变异与代谢综合征有关。[RefSeq 提供,2015 年 12 月]

Sweet, bitter, and umami tastes are transmitted from taste receptors by a specific guanine nucleotide binding protein. The protein encoded by this gene is the alpha subunit of this heterotrimeric G protein, which is found not only in the oral epithelium but also in gut tissues. Variations in this gene have been linked to metabolic syndrome. [provided by RefSeq, Dec 2015]

GNAT3 基因产物(1)

mRNA Protein Name
NM_001102386.3 NP_001095856.1 guanine nucleotide-binding protein G(t) subunit alpha-3

GNAT3 蛋白结构

G-alpha

G-alpha: G-protein alpha subunit (7 - 343)

  • 0
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  • 300
  • 354 a.a.
蛋白主名 其他名称

guanine nucleotide-binding protein G(t) subunit alpha-3

guanine nucleotide binding protein, alpha transducing 3

关联疾病

疾病名称 别名
Invasive Malignant Thymoma

Infiltrating Thymoma

Thymoma Malignant Invasive

Invasive Thymoma And Thymic Carcinoma

Dental Caries

Dental Caries Extending Into Pulp

Dental Caries Of Smooth Surface

Dental Caries Pit And Fissure

Smooth Surface Dental Caries

Dental Decay

Carious Teeth

Dental Cavity

Saprodontia

Teeth Decayed

Tooth Caries

Tooth Decay

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta GNAT3 VGNC VGNC:108410
Rattus norvegicus GNAT3 RGD RGD:727817
Bos taurus GNAT3 VGNC VGNC:29456
Felis catus GNAT3 VGNC VGNC:80052
Mus musculus GNAT3 MGD MGI:3588268
Canis familiaris GNAT3 VGNC VGNC:41309