1. Gene
  2. SERINC2 - serine incorporator 2 Gene

SERINC2 - serine incorporator 2 Gene

中文名称:丝氨酸掺入子 2

种属: Homo sapiens

同用名: TDE2; TDE2L; FKSG84; PRO0899

基因 ID: 347735 | 基因类型: protein coding

关于 SERINC2

Cytogenetic location: 1p35.2 Genomic coordinates (GRCh38): 1:31,409,777-31,434,678 (from NCBI)

This gene has 6 transcripts (splice variants), 276 orthologues and 4 paralogues. Broad expression in urinary bladder (RPKM 35.4), colon (RPKM 35.3) and 17 other tissues.

功能概要

预计参与多个过程,包括磷脂酰丝氨酸代谢过程; CDP-二酰基甘油-丝氨酸 O-磷脂酰转移酶活性的正向调节;和丝氨酸 C-棕榈酰转移酶活性的正调节。位于细胞外外泌体。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to be involved in several processes, including phosphatidylserine metabolic process; positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity; and positive regulation of serine C-palmitoyltransferase activity. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]

SERINC2 基因产物(5)

mRNA Protein Name
NM_001199037.2 NP_001185966.1 serine incorporator 2 isoform 3
NM_001199038.2 NP_001185967.1 serine incorporator 2 isoform 4
NM_001199039.2 NP_001185968.1 serine incorporator 2 isoform 5
NM_018565.4 NP_061035.2 serine incorporator 2 isoform 2
NM_178865.5 NP_849196.2 serine incorporator 2 isoform 1 precursor

SERINC2 蛋白结构

Serinc

Serinc: Serine incorporator (Serinc) (15 - 454)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 455 a.a.
蛋白主名 其他名称

serine incorporator 2

tumor differentially expressed protein 2

关联疾病

疾病名称 别名
Ayme-Gripp Syndrome

AYGRP

Cataracts, Congenital, With Sensorineural Deafness, Down Syndrome-Like Facial Appearance, Short Stature, And Mental Retardation

Aymé-Gripp Syndrome

Fine-Lubinsky Syndrome

Brachycephaly-Deafness-Cataract-Intellectual Disability Syndrome

Brachycephaly-Hearing Loss-Cataract-Intellectual Disability Syndrome

Duane Retraction Syndrome

Stilling-Turk-Duane Syndrome

Duane'S Syndrome

Duane Syndrome

Isolated Duane Retraction Syndrome

Co-Contractive Retraction Syndrome

Duane Anomaly, Isolated

Ocular Retraction Syndrome

Drs

Durs

Autism Spectrum Disorder

Asd

Autism Spectrum Disorders

Autistic Continuum

Pervasive Developmental Disorder

Pervasive Development Disorder

Autistic Behavior

Autistic Disorder

Autistic

Autistic Disorder Of Childhood Onset

Infantile Autism

Childhood Autism

Kanner Syndrome

Pervasive Developmental Delay Nos

Pervasive Developmental Disorder, Not Otherwise Specified

Autism

Autistic Disorder

Autism Susceptibility 1

Childhood Autism

Autistic Disorder Of Childhood Onset

Infantile Autism

Kanner'S Syndrome

Autistic

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Mus musculus SERINC2 MGD MGI:1919132
Bos taurus SERINC2 VGNC VGNC:106920
Macaca mulatta SERINC2 VGNC VGNC:77294
Canis familiaris SERINC2 VGNC VGNC:46020
Rattus norvegicus SERINC2 RGD RGD:1311396
Felis catus SERINC2 VGNC VGNC:65018
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