2. Gene
  3. IGKC - immunoglobulin kappa constant Gene

IGKC - immunoglobulin kappa constant Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：免疫球蛋白κ常数

种属: Homo sapiens

同用名: Km; HCAK1; IGKCD

基因 ID: 3514 | 基因类型: other

关于 IGKC

Cytogenetic location: 2p11.2 Genomic coordinates (GRCh38): 2:88,857,361-88,857,683 (from NCBI)

This gene has 1 transcript (splice variant), 100 orthologues, 82 paralogues and is associated with 1 phenotype.

功能概要

预测启用抗原结合活性和免疫球蛋白受体结合活性。参与视网膜稳态。位于血液微粒和细胞外外泌体中。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable antigen binding activity and immunoglobulin receptor binding activity. Involved in retina homeostasis. Located in blood microparticle and extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]

基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in adaptive immune response IDA
IDA: 通过直接分析推断
11498595 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of IgG immunoglobulin complex IPI
IPI: 通过物理相互作用推断
11498595 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

IGKC 蛋白结构

C1-set

C1-set: Immunoglobulin C1-set domain (12 - 98)

  • 0
  • 100
  • 107 a.a.

IGKC 抗体

目录号 产品名 应用 反应物种
HY-P82251 Human kappa Light Chain Antibody (YA1996) WB, IHC-P, ICC/IF Human

关联疾病

疾病名称 别名
Immunoglobulin Kappa Light Chain Deficiency

Recurrent Infections Associated With Rare Immunoglobulin Isotypes Deficiency

IGKCD

Kappa Chain Deficiency

Kappa Light Chain Deficiency

Kappa-Chain Deficiency

Igg Subclass Deficiency With Iga Subclass Deficiency

Isolated Igg Subclass Deficiency

Selective Igg Subclass Deficiency
Amyloidosis

Amyloid Disease

Amyloid

Amyloid Degeneration

Amyloidosis Nos

Amyloid Deposition

Amyloid Infiltration

Idiopathic Amyloidosis

Hyaloid Degeneration

Lardaceous Degeneration
Plasmacytoma

Solitary Plasmacytoma

Solitary Myeloma

Myeloma - Solitary

Myeloma, Solitary

Plasmacytoma - Category

Solitary Osseous Plasmacytoma

Solitary Plasmacytoma Without Mention Of Remission

Localised Malignant Plasma Cell Tumour Nos

Plasmacytoma Nos
Lymphoma, Mucosa-Associated Lymphoid Type

Malt Lymphoma

Gastric Lymphoma, Primary

Lymphoma, Malt, Somatic

Mucosa-Associated Lymphoid Tissue Lymphoma

Extranodal Marginal Zone B-Cell Lymphoma

MALTOMA

Marginal Zone B-Cell Lymphoma

Mucosa-Associated Lymphatic Tissue Lymphoma

Primary Gastric Lymphoma

Gastric Lymphoma

Familial Primary Gastric Lymphoma
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-171199 In vivo Igkc Mouse Pre-designed siRNA-1 Pre-designed Sets / 否
HY-171200 In vivo Igkc Mouse Pre-designed siRNA-2 Pre-designed Sets / 否
HY-171201 In vivo Igkc Mouse Pre-designed siRNA-3 Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus IGKC RGD RGD:1562743
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