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  2. Cdk14 - cyclin-dependent kinase 14 Gene

Cdk14 - cyclin-dependent kinase 14 Gene

中文名称:细胞周期蛋白依赖性激酶 14

种属: Rattus norvegicus

同用名: Pftk1

基因 ID: 362316 | 基因类型: protein coding

关于 Cdk14

Primary_assembly 4: 28,666,843-29,258,861 forward strand.mRatBN7.2:CM026977.1

This gene has 3 transcripts (splice variants), 201 orthologues, 24 paralogues and is associated with 2 phenotypes. Biased expression in Brain (RPKM 211.8), Lung (RPKM 2.1) and 9 other tissues.

功能概要

预计该基因编码的蛋白可启动细胞周期蛋白结合活性和细胞周期蛋白依赖性蛋白丝氨酸/苏氨酸激酶活性。预计参与有丝分裂细胞周期相变;蛋白质磷酸化;和规范的 Wnt 信号通路的调控。预计位于核质和质膜中。预计是细胞质细胞周期蛋白依赖性蛋白激酶全酶复合物的一部分。预计在胞质溶胶和细胞核中有活性。与人 CDK14(细胞周期蛋白依赖性激酶 14)同源。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable cyclin binding activity and cyclin-dependent protein serine/threonine kinase activity. Predicted to be involved in mitotic cell cycle phase transition; protein phosphorylation; and regulation of canonical Wnt signaling pathway. Predicted to be located in nucleoplasm and plasma membrane. Predicted to be part of cytoplasmic cyclin-dependent protein kinase holoenzyme complex. Predicted to be active in cytosol and nucleus. Orthologous to human CDK14 (cyclin dependent kinase 14). [provided by Alliance of Genome Resources, Apr 2022]

Cdk14 基因产物(3)

mRNA Protein Name
NM_001395583.1 NP_001382512.1 cyclin-dependent kinase 14 isoform 1
NM_001395582.1 NP_001382511.1 cyclin-dependent kinase 14 isoform 1
NM_001395584.1 NP_001382513.1 cyclin-dependent kinase 14 isoform 2

Cdk14 蛋白结构

STKc_PFTAIRE1

STKc_PFTAIRE1: cd07869 (128 - 430)

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  • 469 a.a.
蛋白主名 其他名称

cyclin-dependent kinase 14

PFTAIRE protein kinase 1

cell division protein kinase 14

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cdk14 NCBI NCBI:5218