1. Gene
  2. INHBC - inhibin subunit beta C Gene

INHBC - inhibin subunit beta C Gene

中文名称:抑制素亚基β C

种属: Homo sapiens

同用名: IHBC

基因 ID: 3626 | 基因类型: protein coding

关于 INHBC

Cytogenetic location: 12q13.3 Genomic coordinates (GRCh38): 12:57,434,784-57,452,062 (from NCBI)

This gene has 1 transcript (splice variant), 197 orthologues and 31 paralogues. Restricted expression toward liver (RPKM 50.2).

功能概要

该基因编码 TGF-β (转化生长因子-β) 蛋白质超家族的成员。编码的前原蛋白经过蛋白水解处理,生成同二聚体和异二聚体激活素复合物的亚基。异二聚体复合物可能在抑制激活素 A 信号传导中发挥作用。过表达该基因的转基因小鼠在睾丸、肝脏和前列腺中表现出缺陷。[RefSeq 提供,2016 年 8 月]

This gene encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate a subunit of homodimeric and heterodimeric activin complexes. The heterodimeric complex may function in the inhibition of Activin A signaling. Transgenic mice overexpressing this gene exhibit defects in testis, liver and prostate. [provided by RefSeq, Aug 2016]

INHBC 基因产物(1)

mRNA Protein Name
NM_005538.4 NP_005529.1 inhibin beta C chain preproprotein

INHBC 蛋白结构

TGFb_propeptide

TGFb_propeptide: TGF-beta propeptide (33 - 208)

TGF_beta

TGF_beta: Transforming growth factor beta like domain (245 - 352)

  • 0
  • 100
  • 200
  • 300
  • 352 a.a.
蛋白主名 其他名称

inhibin beta C chain

activin beta-C chain

重组 INHBC 蛋白

目录号 产品名 蛋白编号 纯度
HY-P70383 Inhibin beta C chain/INHBC Protein, Human (HEK293, His) P55103 (T19-S352) ≥95%

直系同源

种属 基因名 来源 基因 ID
Bos taurus INHBC VGNC VGNC:30202
Macaca mulatta INHBC VGNC VGNC:73745
Felis catus INHBC VGNC VGNC:84039
Mus musculus INHBC MGD MGI:105932
Canis familiaris INHBC VGNC VGNC:42023
Rattus norvegicus INHBC RGD RGD:621194
Others INHBC NCBI