2. Gene
  3. IPP - intracisternal A particle-promoted polypeptide Gene

IPP - intracisternal A particle-promoted polypeptide Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：脑池内 A 颗粒促进多肽

种属: Homo sapiens

同用名: KLHL27

基因 ID: 3652 | 基因类型: protein coding

关于 IPP

Cytogenetic location: 1p34.1 Genomic coordinates (GRCh38): 1:45,694,324-45,750,653 (from NCBI)

This gene has 4 transcripts (splice variants), 195 orthologues and 54 paralogues. Ubiquitous expression in thyroid (RPKM 2.7), testis (RPKM 2.4) and 25 other tissues.

功能概要

由该基因编码的蛋白质是 kelch 蛋白质家族的成员，其特征是与肌动蛋白相互作用的 50 个氨基酸重复序列。已经描述了转录变体，但尚未确定其全长性质。[RefSeq 提供，2008 年 7 月]

The protein encoded by this gene is a member of the kelch family of proteins, which is characterized by a 50 amino acid repeat which interacts with actin. Transcript variants have been described but their full-length nature has not been determined. [provided by RefSeq, Jul 2008]

IPP 基因产物(2)

mRNA Protein Name
NM_001145349.2 NP_001138821.1 actin-binding protein IPP isoform 2
NM_005897.3 NP_005888.1 actin-binding protein IPP isoform 1
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

IPP 蛋白结构

BTB

BTB: BTB/POZ domain (28 - 133)

BACK

BACK: BTB And C-terminal Kelch (139 - 240)

Kelch_1

Kelch_1: Kelch motif (289 - 329)

Kelch_1

Kelch_1: Kelch motif (332 - 377)

Kelch_1

Kelch_1: Kelch motif (379 - 423)

Kelch_1

Kelch_1: Kelch motif (427 - 471)

Kelch_1

Kelch_1: Kelch motif (474 - 519)

Kelch_1

Kelch_1: Kelch motif (522 - 572)

  • 0
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  • 500
  • 584 a.a.
蛋白主名 其他名称

actin-binding protein IPP

kelch-like family member 27

关联疾病

疾病名称 别名
Peroneal Nerve Paralysis

Peroneal Nerve Palsy
Progressive Myoclonus Epilepsy 10

Early-Onset Lafora Body Disease

Epm10
Villonodular Synovitis

Pigmented Villonodular Synovitis
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Clinical Phase
生物活性分子 (1)
目录号 产品名 作用方式
纯度 Phase
HY-105037A Forigerimod TFA Inhibitor 98.89% Phase 3
Pre-clinical Phase
生物活性分子 (7)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-110063 4-IPP Inhibitor 99.46% 否
HY-130573A DMAPP triammonium ≥95.0% 否
HY-105037 Forigerimod Inhibitor / 否
HY-126825 NE21650 / 否
HY-130573 DMAPP / 否
HY-RS06873 IPP Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-126404 Casein hydrolysate Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus IPP RGD RGD:1306299
Felis catus IPP VGNC VGNC:67816
Macaca mulatta IPP VGNC VGNC:73754
Canis familiaris IPP VGNC VGNC:42070
Bos taurus IPP VGNC VGNC:30247
Mus musculus IPP MGD MGI:96581
Others IPP NCBI
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