Pik3cd - phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta Gene

中文名称：磷脂酰肌醇 4 ,5-二磷酸 3-激酶，催化亚基 δ

种属: Rattus norvegicus

关于 Pik3cd

功能概要

预测该基因编码的蛋白具有 1-磷脂酰肌醇 3-激酶活性和 1-磷脂酰肌醇 4-磷酸 3-激酶活性。参与基因表达的负调控。预测位于胞质溶胶中。预计是磷脂酰肌醇 3-激酶复合物的一部分。预计在细胞质和质膜中有活性。该基因的人类直系同源物与结直肠癌有关；子宫内膜癌;和免疫缺陷 14. 与人 PIK3CD（磷脂酰肌醇 4,5-二磷酸 3-激酶催化亚基三角洲）同源。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable 1-phosphatidylinositol-3-kinase activity and 1-phosphatidylinositol-4-phosphate 3-kinase activity. Involved in negative regulation of gene expression. Predicted to be located in cytosol. Predicted to be part of phosphatidylinositol 3-kinase complex. Predicted to be active in cytoplasm and plasma membrane. Human ortholog(s) of this gene implicated in colorectal cancer; endometrial cancer; and immunodeficiency 14. Orthologous to human PIK3CD (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta). [provided by Alliance of Genome Resources, Apr 2022]