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  3. Bmx - BMX non-receptor tyrosine kinase Gene

Bmx - BMX non-receptor tyrosine kinase Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：BMX 非受体酪氨酸激酶

种属: Rattus norvegicus

同用名: RGD1565643

基因 ID: 367786 | 基因类型: protein coding

关于 Bmx

Primary_assembly X: 30,227,251-30,289,993 forward strand.mRatBN7.2:CM026994.1

This gene has 1 transcript (splice variant), 137 orthologues, 32 paralogues and is associated with 3 phenotypes. Biased expression in Lung (RPKM 13.7), Heart (RPKM 9.) and 9 other tissues.

功能概要

预计该基因编码的蛋白可启动非跨膜蛋白酪氨酸激酶活性。预计参与B细胞受体信号通路；适应性免疫反应；和肽基酪氨酸自磷酸化。预测位于核质和褶皱膜中。与人 BMX（BMX 非受体酪氨酸激酶）同源。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable non-membrane spanning protein tyrosine kinase activity. Predicted to be involved in B cell receptor signaling pathway; adaptive immune response; and peptidyl-tyrosine autophosphorylation. Predicted to be located in nucleoplasm and ruffle membrane. Orthologous to human BMX (BMX non-receptor tyrosine kinase). [provided by Alliance of Genome Resources, Apr 2022]

Bmx 基因产物(1)

mRNA Protein Name
NM_001109016.1 NP_001102486.1 cytoplasmic tyrosine-protein kinase BMX

Bmx 蛋白结构

PH_Btk

PH_Btk: cd01238 (24 - 150)

SH2_Tec_Bmx

SH2_Tec_Bmx: cd10399 (268 - 373)

PKc_like

PKc_like: cl21453 (391 - 646)

  • 0
  • 200
  • 400
  • 600
  • 655 a.a.
蛋白主名 其他名称

cytoplasmic tyrosine-protein kinase BMX

相关产品

Clinical Phase
生物活性分子 (2)
目录号 产品名 作用方式
纯度 Phase
HY-130574 MnTE-2-PyP chloride ≥95.0% Phase 2
HY-111553 TAS0728 Inhibitor 99.15% Phase 1
Pre-clinical Phase
生物活性分子 (11)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-80002 BMX-IN-1 Inhibitor 99.04% 否
HY-101267 CHMFL-BMX-078 Inhibitor ≥98.0% 否
HY-145373 BMS-986143 Inhibitor / 否
HY-117900A (Rac)-PF-06250112 / 否
HY-148585 BTK-IN-22 Inhibitor / 否
HY-148594 BTK-IN-23 Inhibitor / 否
HY-RS01557 BMX Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS01558 Bmx Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS01559 Bmx Rat Pre-designed siRNA Set A Pre-designed Sets / 否
HY-125662A BMX-001 Inhibitor / 否
HY-117900 PF-06250112 Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Bmx NCBI NCBI:660
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