ITGA9 - integrin subunit alpha 9 Gene

中文名称：整合素亚基 alpha 9

种属: Homo sapiens

同用名: RLC; ITGA4L; ALPHA-RLC

基因 ID: 3680 | 基因类型: protein coding

关于 ITGA9

Cytogenetic location: 3p22.2 Genomic coordinates (GRCh38): 3:37,452,141-37,823,507 (from NCBI)

This gene has 4 transcripts (splice variants), 237 orthologues and 17 paralogues. Ubiquitous expression in thyroid (RPKM 11.9), spleen (RPKM 11.4) and 24 other tissues.

功能概要

该基因编码 alpha 整合素。整联蛋白是由介导细胞-细胞和细胞-基质粘附的α链和β链组成的异二聚体整合膜糖蛋白。由该基因编码的蛋白质与 β1 链结合时，会形成一种整合素，它是 VCAM1、细胞趋化素和骨桥蛋白的受体。已发现该基因的表达在小细胞肺癌中上调。[RefSeq 提供，2008 年 7 月]

This gene encodes an alpha Integrin. Integrins are heterodimeric integral membrane glycoproteins composed of an alpha chain and a beta chain that mediate cell-cell and cell-matrix adhesion. The protein encoded by this gene, when bound to the beta 1 chain, forms an Integrin that is a receptor for VCAM1, cytotactin and osteopontin. Expression of this gene has been found to be upregulated in small cell lung cancers. [provided by RefSeq, Jul 2008]

ITGA9 基因产物(1)

mRNA	Protein	Name
NM_002207.3	NP_002198.2	integrin alpha-9 precursor

基因本体论

分子功能
生物过程
细胞组分

分子功能 GO 注释	逻辑证据	参考文献	来源
enables protein binding	IPI IPI: 通过物理相互作用推断	35802072	GOA

生物过程 GO 注释	逻辑证据	参考文献	来源
acts upstream of or within cell adhesion	IGI IGI: 通过遗传相互作用推断	21060781	GOA
involved in negative regulation of vasoconstriction	IMP IMP: 通过突变表型推断	35802072	GOA

细胞组分 GO 注释	逻辑证据	参考文献	来源
part of integrin alpha9-beta1 complex	IPI IPI: 通过物理相互作用推断	25748048	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

ITGA9 蛋白结构

VCBS

Integrin_alpha2

0
200
400
600
800
1035 a.a.

蛋白主名

其他名称

integrin alpha-9

integrin alpha-RLC

ITGA9 抗体

目录号	产品名	应用	反应物种
HY-P81915	Integrin alpha 9 Antibody (YA1660)	WB, IHC-P	Human, Mouse, Rat

关联疾病

疾病名称

别名

Chylothorax, Congenital

Congenital Chylothorax

Hydrothorax, Congenital

Hereditary Lymphedema Ia

Lmph1a	Lymphedema, Hereditary, Ia
Milroy Disease

Lynch Syndrome

Hereditary Nonpolyposis Colon Cancer	Hereditary Nonpolyposis Colorectal Cancer
Hereditary Nonpolyposis Colorectal Carcinoma	Hereditary Nonpolyposis Colorectal Neoplasms
Familial Nonpolyposis Colon Cancer	Hnpcc
Coca 1	Hereditary Defective Mismatch Repair Syndrome
Hereditary Non-Polyposis Colon Cancer	Hereditary Non-Polyposis Colon Cancer Syndrome
Hereditary Non-Polyposis Colorectal Cancer	Hereditary Non-Polyposis Colorectal Cancer Syndrome
Hereditary Nonpolyposis Colon Cancer Syndrome	Hereditary Nonpolyposis Colorectal Cancer Syndrome
Hereditary Nonpolyposis Colorectal Neoplasm	Hnpcc - Hereditary Nonpolyposis Colon Cancer
Cancer Family Syndrome	Familial Nonpolyposis Colorectal Cancer
Colon Cancer, Familial Nonpolyposis	Colorectal Neoplasms, Hereditary Nonpolyposis
Cancer, Colorectal, Nonpolyposis, Hereditary	Colorectal Cancer, Hereditary Nonpolyposis, Type 1

Lymphedema-Distichiasis Syndrome

Lymphedema With Distichiasis	Lymphedema-Distichiasis Syndrome With Renal Disease And Diabetes Mellitus
LPHDST	Distichiasis-Lymphedema Syndrome
Lymphedema Distichiasis Syndrome	Hereditary Lymphedema-Distichiasis Syndrome
Lymphedema Distichiasis

Hypotrichosis-Lymphedema-Telangiectasia Syndrome

HLTS	Hypotrichosis Lymphedema Telangiectasia Syndrome
Hypotrichosis-Lymphedema-Telangiectasia-Membranoproliferative Glomerulonephritis Syndrome	Hypotrichosis-Lymphedema-Telangiectasia-Renal Defect Syndrome

Yellow Nail Syndrome

Yns	Lymphedema And Yellow Nails
Lymphedema With Yellow Nails	Lymphedema-Yellow Nails
LYYN	Hereditary Lymphedema And Yellow Nails
Hereditary Lymphoedema And Yellow Nails

Hereditary Lymphedema

Milroy Disease

Hereditary Lymphedema I

Lymphedema	Hereditary Lymphedema Type I
Congenital Primary Lymphedema	Lmph1
Milroy Disease	Nonne-Milroy Lymphedema
Pcl	Lymphedema Hereditary Type 1

Hennekam Syndrome

Hennekam Lymphangiectasia Lymphedema Syndrome	Hennekam Lymphangiectasia-Lymphedema Syndrome
Lymphedema-Lymphangiectasia-Intellectual Disability Syndrome	Lymphedem-Lymphangiectasia-Intellectual Disability Syndrome
Intestinal Lymphagiectasia Lymphedema Intellectual Deficit Syndrome	Lymphangiectasies And Lymphedema Hennekam Type
Generalized Lymphatic Dysplasia	Intestinal Lymphagiectasia-Lymphedema-Mental Retardation Syndrome

Lung Cancer

Lung Carcinoma	Non-Small Cell Lung Carcinoma
Lung Cancer, Susceptibility To	Lung Cancer, Protection Against
Adenocarcinoma Of Lung, Somatic	Adenocarcinoma Of Lung, Response To Tyrosine Kinase Inhibitor In
Nonsmall Cell Lung Cancer	Lung Neoplasm
Carcinoma Of Lung	Lung Non-Small Cell Carcinoma
Non-Small Cell Lung Cancer	Nsclc
Lung Neoplasms	Malignant Neoplasm Of Lung
Alveolar Cell Carcinoma	Nonsmall Cell Lung Cancer, Somatic
Nonsmall Cell Lung Cancer, Response To Tyrosine Kinase Inhibitor In	Nonsmall Cell Lung Cancer, Susceptibility To
Lung Cancer, Somatic	Lung Cancer, Resistance To
Cancer Of Lung	Cancer Of Bronchus
Cancer Of The Lung	Lung Malignancies
Lung Malignant Tumors	Malignant Lung Tumor
Malignant Tumor Of Lung	Pulmonary Cancer
Pulmonary Carcinoma	Pulmonary Neoplasms
Respiratory Carcinoma	LNCR
Adenocarcinoma Of Lung	Neoplasm Of Lung
Cancer Lung	Carcinoma Non-Small Cell Lung
Carcinoma, Non-Small-Cell Lung	Lung Cancers
Lung Carcinomas	Cancer, Lung
Cancer, Lung, Non-Small Cell	Primary Malignant Neoplasm Of Lung
Bronchioloalveolar Adenocarcinoma

Arrhythmogenic Right Ventricular Cardiomyopathy

Arrhythmogenic Right Ventricular Dysplasia	Arvc
Arvd	Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy
Arvc Cardiomyopathy	Arrhythmogenic Right Ventricular Cardiomyopathy-Dysplasia
Arvd/C	Right Ventricular Dysplasia, Arrhythmogenic
Ventricular Dysplasia, Right, Arrhythmogenic	Cardiomyopathy, Ventricular, Right, Arrhythmogenic
Dysplasia, Arrhythmogenic Right Ventricular

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS06956	ITGA9 Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Felis catus	ITGA9	VGNC	VGNC:97469
Bos taurus	ITGA9	VGNC	VGNC:30320
Canis familiaris	ITGA9	VGNC	VGNC:49914
Macaca mulatta	ITGA9	VGNC	VGNC:82165
Rattus norvegicus	ITGA9	RGD	RGD:1311191
Mus musculus	ITGA9	MGD	MGI:104756

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

ITGA9 - integrin subunit alpha 9 Gene

关于 ITGA9

功能概要

ITGA9 基因产物(1)

ITGA9 蛋白结构

ITGA9 抗体

关联疾病

直系同源

热门区域

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ITGA9 - integrin subunit alpha 9 Gene

关于 ITGA9

功能概要

ITGA9 基因产物(1)

ITGA9 蛋白结构

ITGA9 抗体

关联疾病

相关产品

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z