2. Gene
  3. PEAR1 - platelet endothelial aggregation receptor 1 Gene

PEAR1 - platelet endothelial aggregation receptor 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：血小板内皮聚集受体 1

种属: Homo sapiens

同用名: JEDI; MEGF12

基因 ID: 375033 | 基因类型: protein coding

关于 PEAR1

Cytogenetic location: 1q23.1 Genomic coordinates (GRCh38): 1:156,893,718-156,916,429 (from NCBI)

This gene has 7 transcripts (splice variants), 114 orthologues and 1 paralogue. Broad expression in fat (RPKM 9.8), placenta (RPKM 6.3) and 24 other tissues.

功能概要

PEAR1 是一种血小板受体，在血小板-血小板接触形成时发出信号，独立于血小板激活并继发于血小板聚集 (Nanda 等人，2005 [PubMed 15851471]) 。[OMIM 提供，2008 年 3 月]

PEAR1 is a platelet receptor that signals upon the formation of platelet-platelet contacts independent of platelet activation and secondary to platelet aggregation (Nanda et al., 2005 [PubMed 15851471]).[supplied by OMIM, Mar 2008]

PEAR1 基因产物(3)

mRNA Protein Name
NM_001080471.3 NP_001073940.1 platelet endothelial aggregation receptor 1 isoform 1 precursor
NM_001353682.2 NP_001340611.1 platelet endothelial aggregation receptor 1 isoform 2
NM_001353683.2 NP_001340612.1 platelet endothelial aggregation receptor 1 isoform 2

PEAR1 蛋白结构

hEGF

hEGF: Human growth factor-like EGF (119 - 131)

hEGF

hEGF: Human growth factor-like EGF (290 - 302)

Laminin_EGF

Laminin_EGF: Laminin EGF domain (319 - 358)

hEGF

hEGF: Human growth factor-like EGF (423 - 434)

hEGF

hEGF: Human growth factor-like EGF (552 - 563)

Laminin_EGF

Laminin_EGF: Laminin EGF domain (622 - 665)

hEGF

hEGF: Human growth factor-like EGF (679 - 691)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 1037 a.a.
蛋白主名 其他名称

platelet endothelial aggregation receptor 1

multiple EGF-like domains protein 12

PEAR1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
PEAR1 Q5VY43 KRTAP4-5 Homo sapiens Q9BYR2
Validated Y2H
32296183
种属内
PEAR1 Q5VY43 NUFIP2 Homo sapiens Q7Z417
Validated Y2H
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Aspirin Allergy

Acetylsalicylic Acid Allergy

Asa Allergy
Lipoprotein Quantitative Trait Locus

Coronary Artery Disease

Coronary Artery Anomaly

Coronary Artery Disease, Susceptibility To

Myocardial Ischemia

Congenital Anomaly Of Coronary Artery

Coronary Arteriosclerosis

Coronary Disease

Coronary Heart Disease

Coronary Artery Disorder

LPAQTL

Lpa Deficiency, Congenital

Coronary Artery Abnormality

Coronary Artery Anomaly, Congenital

Chd

Coronary Syndrome

Congenital Malformations Of Coronary Vessels

Malformation Of Coronary Vessels

Congenital Coronary Artery Anomaly

Congenital Coronary Artery Deformity

Congenital Coronary Artery Disorder

Abnormal Coronary Artery

Congenital Coronary Artery Malposition

Congenital Coronary Disease

Congenital Anomaly Of Coronary Arteries
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS10312 PEAR1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus PEAR1 MGD MGI:1920432
Felis catus PEAR1 VGNC VGNC:64108
Rattus norvegicus PEAR1 RGD RGD:1305653
Canis familiaris PEAR1 VGNC VGNC:44408
Macaca mulatta PEAR1 VGNC VGNC:106468
Bos taurus PEAR1 VGNC VGNC:32734
Others PEAR1 NCBI
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z