MAN1A1 - mannosidase alpha class 1A member 1 Gene

中文名称：甘露糖苷酶 alpha 1A 类成员 1

种属: Homo sapiens

同用名: MAN9; HUMM3; HUMM9

基因 ID: 4121 | 基因类型: protein coding

关于 MAN1A1

Cytogenetic location: 6q22.31 Genomic coordinates (GRCh38): 6:119,177,205-119,350,605 (from NCBI)

This gene has 1 transcript (splice variant), 222 orthologues and 6 paralogues. Ubiquitous expression in fat (RPKM 62.7), liver (RPKM 46.9) and 25 other tissues.

功能概要

该基因编码 I 类哺乳动物高尔基体 1,2-甘露糖苷酶，这是一种 II 型跨膜蛋白。这种蛋白质催化来自肽结合的 Man (9) -GlcNAc (2) 寡糖的三个末端甘露糖残基的水解，属于糖基水解酶家族 47。[RefSeq 提供，2012 年 7 月]

This gene encodes a class I mammalian Golgi 1,2-mannosidase which is a type II transmembrane protein. This protein catalyzes the hydrolysis of three terminal mannose residues from peptide-bound Man(9)-GlcNAc(2) oligosaccharides and belongs to family 47 of glycosyl hydrolases. [provided by RefSeq, Jul 2012]

MAN1A1 基因产物(1)

mRNA	Protein	Name
NM_005907.4	NP_005898.2	mannosyl-oligosaccharide 1,2-alpha-mannosidase IA

MAN1A1 蛋白结构

Glyco_hydro_47

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653 a.a.

蛋白主名

其他名称

mannosyl-oligosaccharide 1,2-alpha-mannosidase IA

Man9-mannosidase

关联疾病

疾病名称

别名

Congenital Disorder Of Glycosylation, Type In

Congenital Disorder Of Glycosylation	CDG1N
Congenital Disorders Of Glycosylation	Cdg In
Cdgin	Congenital Disorder Of Glycosylation 1n
Carbohydrate-Deficient Glycoprotein Syndrome	Cdg
Rft1-Cdg	Cdg-In
Congenital Disorder Of Glycosylation Type In	Carbohydrate Deficient Glycoprotein Syndrome
Cdg Syndrome	Congenital Disorder Of Glycosylation In
Carbohydrate-Deficient Glycoprotein Syndromes	Cdg Syndrome Type In
Carbohydrate Deficient Glycoprotein Syndrome Type In	Congenital Disorder Of Glycosylation Type 1n
Man5glcnac2-Pp-Dol Flippase Deficiency	Glycosylation, Congenital Disorder Of
Glycosylation, Congenital Disorder Of, Type In

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-E70304	Mannosyl-oligosaccharide 1,2-α-mannosidase IA		/	否
HY-RS08004	MAN1A1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	否
HY-RS08006	MAN1B1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	否
HY-RS08007	MAN1C1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Mus musculus	MAN1A1	MGD	MGI:104677
Bos taurus	MAN1A1	VGNC	VGNC:31161
Felis catus	MAN1A1	VGNC	VGNC:68144
Canis familiaris	MAN1A1	VGNC	VGNC:42942
Rattus norvegicus	MAN1A1	RGD	RGD:1310891
Macaca mulatta	MAN1A1	VGNC	VGNC:74483

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

MAN1A1 - mannosidase alpha class 1A member 1 Gene

关于 MAN1A1

功能概要

MAN1A1 基因产物(1)

MAN1A1 蛋白结构

关联疾病

直系同源

热门区域

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MAN1A1 - mannosidase alpha class 1A member 1 Gene

关于 MAN1A1

功能概要

MAN1A1 基因产物(1)

MAN1A1 蛋白结构

关联疾病

相关产品

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z