PAFAH2 - platelet activating factor acetylhydrolase 2 Gene

中文名称：血小板活化因子乙酰水解酶 2

种属: Homo sapiens

同用名: HSD-PLA2

关于 PAFAH2

功能概要

该基因编码血小板活化因子乙酰水解酶亚型 2，这是一种单亚基胞内酶，可催化去除血小板活化因子 SN-2 位置的乙酰基 (鉴定为 1-O-alkyl-2-acetyl-sn -甘油基-3-磷酸胆碱) 。然而，这种脂肪酶表现出比简单的血小板活化因子更广泛的底物特异性。存在另外两种细胞内血小板活化因子乙酰水解酶同种型，它们都是多亚基酶。此外，该酶还有一种单亚基血清亚型。[RefSeq 提供，2008 年 7 月]

This gene encodes platelet-activating factor acetylhydrolase isoform 2, a single-subunit intracellular Enzyme that catalyzes the removal of the acetyl group at the SN-2 position of platelet-activating factor (identified as 1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine). However, this Lipase exhibits a broader substrate specificity than simply platelet activating factor. Two Other isoforms of intracellular platelet-activating factor acetylhydrolase exist, and both are multi-subunit Enzymes. Additionally, there is a single-subunit serum isoform of this Enzyme. [provided by RefSeq, Jul 2008]