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  3. TAS2R1 - taste 2 receptor member 1 Gene

TAS2R1 - taste 2 receptor member 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：味觉 2 受体成员 1

种属: Homo sapiens

同用名: T2R1; TRB7

基因 ID: 50834 | 基因类型: protein coding

关于 TAS2R1

Cytogenetic location: 5p15.31-p15.2 Genomic coordinates (GRCh38): 5:9,627,347-9,903,876 (from NCBI)

This gene has 3 transcripts (splice variants), 162 orthologues and 23 paralogues.

功能概要

该基因编码候选味觉受体家族的一个成员，这些味觉受体是 G 蛋白偶联受体超家族的成员，由舌头和上颚上皮细胞的味觉受体细胞特异性表达。这种无内含子的味觉受体基因编码一种 7 次跨膜受体蛋白，作为苦味受体发挥作用。该基因被映射到染色体 5p15，这是控制苦味化合物 6-n-propyl-2-thiouracil 检测的遗传位点 (PROP) 的位置。[RefSeq 提供，2008 年 7 月]

This gene encodes a member of a family of candidate taste receptors that are members of the G protein-coupled receptor superfamily and that are specifically expressed by Taste Receptor cells of the tongue and palate epithelia. This intronless Taste Receptor gene encodes a 7-transmembrane receptor protein, functioning as a bitter Taste Receptor. This gene is mapped to chromosome 5p15, the location of a genetic locus (PROP) that controls the detection of the bitter compound 6-n-propyl-2-thiouracil. [provided by RefSeq, Jul 2008]

TAS2R1 基因产物(2)

mRNA Protein Name
NM_001386348.1 NP_001373277.1 taste receptor type 2 member 1 isoform 2
NM_019599.3 NP_062545.1 taste receptor type 2 member 1 isoform 1

TAS2R1 蛋白结构

TAS2R

TAS2R: Taste receptor protein (TAS2R) (1 - 296)

  • 0
  • 100
  • 200
  • 299 a.a.
蛋白主名 其他名称

taste receptor type 2 member 1

taste receptor, family B, member 7

关联疾病

疾病名称 别名
Cri-Du-Chat Syndrome

5p Deletion Syndrome

5p Partial Monosomy Syndrome

Monosomy 5p

Cat Cry Syndrome

Chromosome 5p Deletion Syndrome

Cri Du Chat Syndrome

5p- Syndrome

5p Minus Syndrome

Chromosome 5p- Syndrome

Chromosome 5 Short Arm Deletion Syndrome

Chromosome 5p Deletion

Deletion 5p

Cri Du Chat

5p Partial Deletion Syndrome

Partial Deletion Of Short Arm Of Chromosome 5 Syndrome
Autism

Autistic Disorder

Autism Susceptibility 1

Childhood Autism

Autistic Disorder Of Childhood Onset

Infantile Autism

Kanner'S Syndrome

Autistic
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS14215 TAS2R1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus TAS2R1 RGD RGD:620733
Canis familiaris TAS2R1 VGNC VGNC:47114
Felis catus TAS2R1 VGNC VGNC:65959
Macaca mulatta TAS2R1 VGNC VGNC:110429
Mus musculus TAS2R1 MGD MGI:2681253
Bos taurus TAS2R1 VGNC VGNC:35609
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