2. Gene
  3. Il22 - interleukin 22 Gene

Il22 - interleukin 22 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: IL-22; If2b1; Iltif; IL-22a; ILTIFa

基因 ID: 50929 | 基因类型: protein coding

关于 Il22

功能概要

Predicted to enable cytokine activity. Acts upstream of or within several processes, including negative regulation of inflammatory response; Reactive Oxygen Species metabolic process; and regulation of tyrosine phosphorylation of STAT protein. Predicted to be located in extracellular space. Is expressed in retina and skin. Used to study liposarcoma. Human ortholog(s) of this gene implicated in asthma. Orthologous to human IL22 (interleukin 22). [provided by Alliance of Genome Resources, Apr 2022]

Il22 基因产物(1)

mRNA Protein Name
NM_016971.2 NP_058667.1 interleukin-22 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables cytokine activity IDA
IDA: 通过直接分析推断
28811323 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
12700595 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of inflammatory response IDA
IDA: 通过直接分析推断
28811323 MGI
acts upstream of or within negative regulation of inflammatory response IMP
IMP: 通过突变表型推断
23075849 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
16982811 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IGI
IGI: 通过遗传相互作用推断
16982811 MGI
acts upstream of or within reactive oxygen species metabolic process IDA
IDA: 通过直接分析推断
12700595 MGI
acts upstream of or within regulation of tyrosine phosphorylation of STAT protein IDA
IDA: 通过直接分析推断
12700595 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in extracellular space IDA
IDA: 通过直接分析推断
28811323 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

interleukin-22

IL-10-related T-cell-derived-inducible factor

IL-TIF alpha

ILTIF alpha

interferon 2b1

interleukin 10-related T cell-derived inducible factor

interleukin-22a

重组 Il22 蛋白

目录号 产品名 蛋白编号 纯度
HY-P7079 IL-22 Protein, Mouse Q9JJY9 (L34-V179) ≥95%
HY-P72793 IL-22 Protein, Mouse (CHO) Q9JJY9 (L34-V179) ≥95%
HY-P78150 IL-22 Protein, Mouse (His-Avi) Q9JJY9 (L34-V179) ≥95%
HY-P7079A IL-22 Protein, Mouse (His) Q9JJY9 (L34-V179) ≥95%
HY-P7079AF Animal-Free IL-22 Protein, Mouse (His) Q9JJY9 (L34-V179) ≥95%

相关产品

Clinical Phase
抗体抑制剂 (2)
目录号 产品名 作用方式
纯度 Phase
HY-P99244 Fezakinumab 99.30% Phase 2
HY-P99919 Efmarodocokin alfa Activator / Phase 1
Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-133552 RORγt Inverse agonist 10 Antagonist 99.13% 否
HY-162490 TF-S14 Inhibitor / 否
HY-RS06736 IL22 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS06737 IL22RA1 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS06738 IL22RA2 Human Pre-designed siRNA Set A Pre-designed Sets / 否
抗体抑制剂 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P990016 Temtokibart Inhibitor 99.23% 否
HY-P99917 Eflepedocokin alfa Activator / 否
HY-P990735 Donzakimig / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Il22 NCBI NCBI:50616
Canis familiaris Il22 NCBI NCBI:481153
Macaca fascicularis Il22 NCBI NCBI:102129310
Rattus norvegicus Il22 NCBI NCBI:500836
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