MZB1 - marginal zone B and B1 cell specific protein Gene

中文名称：边缘区 B 和 B1 细胞特异性蛋白

种属: Homo sapiens

同用名: PACAP; pERp1; MEDA-7

基因 ID: 51237 | 基因类型: protein coding

关于 MZB1

Cytogenetic location: 5q31.2 Genomic coordinates (GRCh38): 5:139,387,467-139,389,913 (from NCBI)

This gene has 8 transcripts (splice variants) and 102 orthologues. Biased expression in lymph node (RPKM 68.4), urinary bladder (RPKM 65.2) and 13 other tissues.

功能概要

参与细胞群增殖的正调控。位于细胞质和胞外区。 [由基因组资源联盟提供，2022 年 4 月]

Involved in positive regulation of cell population proliferation. Located in cytoplasm and extracellular region. [provided by Alliance of Genome Resources, Apr 2022]

MZB1 基因产物(1)

mRNA	Protein	Name
NM_016459.4	NP_057543.2	marginal zone B- and B1-cell-specific protein precursor

基因本体论

分子功能
生物过程
细胞组分

分子功能 GO 注释	逻辑证据	参考文献	来源
enables protein binding	IPI IPI: 通过物理相互作用推断	11350957	GOA

生物过程 GO 注释	逻辑证据	参考文献	来源
involved in positive regulation of cell population proliferation	IDA IDA: 通过直接分析推断	21688198	GOA

细胞组分 GO 注释	逻辑证据	参考文献	来源
located in cytoplasm	IDA IDA: 通过直接分析推断	11350957	GOA
located in extracellular region	IDA IDA: 通过直接分析推断	21688198	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

MZB1 蛋白结构

DUF3456

0
100
189 a.a.

蛋白主名

其他名称

marginal zone B- and B1-cell-specific protein

HSPC190

MZB1 蛋白互作信息

分类	蛋白名称	蛋白编号	互作蛋白	互作蛋白种属	互作蛋白编号	实验方法	参考文献
种属内	MZB1	Q8WU39	TSG101	Homo sapiens	Q99816	Validated Y2H	32296183

种属间: 跨种属相互作用 种属内: 同种属相互作用

重组 MZB1 蛋白

目录号	产品名	蛋白编号	纯度
HY-P77094	MZB1/PERP1 Protein, Human (HEK293, Fc)	Q8WU39-1 (D23-T185)	≥95%
HY-P77095	MZB1/PERP1 Protein, Human (HEK293, His)	Q8WU39-1 (D23-T185)	≥95%

关联疾病

疾病名称

别名

Mooren'S Ulcer

Mooren Ulcer

Moorens Ulcer

Isolated Growth Hormone Deficiency

Congenital Ighd	Congenital Isolated Gh Deficiency
Congenital Isolated Growth Hormone Deficiency	Non-Acquired Isolated Growth Hormone Deficiency
Pituitary Dwarfism	Dwarfism, Pituitary
Isolated Somatotropin Deficiency	Isolated Congenital Growth Hormone Deficiency
Familial Isolated Growth Hormone Deficiency	Ighd
Dwarfism, Growth Hormone Deficiency	Growth Hormone Deficiency Dwarfism
Isolated Gh Deficiency	Isolated Hgh Deficiency
Isolated Human Growth Hormone Deficiency	Isolated Somatotropin Deficiency Disorder
Dwarfism Pituitary

Gastric Cancer

Stomach Cancer	Gastric Carcinoma
Stomach Carcinoma	Gastric Cancer, Somatic
Gastric Neoplasm	Carcinoma Of Stomach
Stomach Neoplasms	Malignant Neoplasm Of Stomach
Gastric Cancer Risk After H. Pylori Infection	Cancer Of The Stomach
Adult Stomach Cancer	Adult Stomach Carcinoma
GASC	Gastric Cancer Intestinal
Gastric Cancers	Gastric Carcinomas
Cancer, Gastric	Stomach Neoplasm
Malignant Neoplasm Of Body Of Stomach	Malignant Tumor Of Lesser Curve Of Stomach
Gastrocarcinoma Of Unspecified Site	Leather Bottle Stomach
Carcinoma Of Fundus Of Stomach	Cancer Of Fundus Of Stomach
Primary Malignant Neoplasm Of Body Of Stomach	Cancer Of Body Of Stomach
Primary Malignant Neoplasm Of Pyloric Antrum	Pyloric Antrum Cancer
Malignant Tumour Of Stomach

Chromosome 22q11.2 Deletion Syndrome, Distal

22q11.2 Deletion Syndrome	Autosomal Dominant Opitz G/Bbb Syndrome
Catch22	Cayler Cardiofacial Syndrome
Conotruncal Anomaly Face Syndrome	Digeorge Syndrome
Sedlackova Syndrome	Shprintzen Syndrome
Velocardiofacial Syndrome	22q11.2 Distal Deletion Syndrome
Distal 22q11.2 Microdeletion Syndrome	22q11.2ds
Vcfs	Velo-Cardio-Facial Syndrome
Distal Chromosome 22q11.2 Deletion Syndrome	Chromosome 22q11.2 Deletion Syndrome Distal
Chromosome 22q11.2 Deletion Syndrome	Deletion 22q11.2 Syndrome
22q11ds	Catch 22
Digeorge Sequence	Microdeletion 22q11.2
Monosomy 22q11	Takao Syndrome
Distal Del(22)(Q11.2)	Distal Monosomy 22q11.2
Catch 22 Syndrome	Chromosome Deletion Syndrome 22q11.2, Distal

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS08976	MZB1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Canis familiaris	MZB1	VGNC	VGNC:43593
Felis catus	MZB1	VGNC	VGNC:63699
Mus musculus	MZB1	MGD	MGI:1917066
Rattus norvegicus	MZB1	RGD	RGD:1310251
Bos taurus	MZB1	VGNC	VGNC:31849
Macaca mulatta	MZB1	VGNC	VGNC:110450
Others	MZB1	NCBI

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

MZB1 - marginal zone B and B1 cell specific protein Gene

关于 MZB1

功能概要

MZB1 基因产物(1)

MZB1 蛋白结构

MZB1 蛋白互作信息

重组 MZB1 蛋白

关联疾病

直系同源

热门区域

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MZB1 - marginal zone B and B1 cell specific protein Gene

关于 MZB1

功能概要

MZB1 基因产物(1)

MZB1 蛋白结构

MZB1 蛋白互作信息

重组 MZB1 蛋白

关联疾病

相关产品

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z