2. Gene
  3. MZB1 - marginal zone B and B1 cell specific protein Gene

MZB1 - marginal zone B and B1 cell specific protein Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：边缘区 B 和 B1 细胞特异性蛋白

种属: Homo sapiens

同用名: PACAP; pERp1; MEDA-7

基因 ID: 51237 | 基因类型: protein coding

关于 MZB1

Cytogenetic location: 5q31.2 Genomic coordinates (GRCh38): 5:139,387,467-139,389,913 (from NCBI)

This gene has 8 transcripts (splice variants) and 102 orthologues. Biased expression in lymph node (RPKM 68.4), urinary bladder (RPKM 65.2) and 13 other tissues.

功能概要

参与细胞群增殖的正调控。位于细胞质和胞外区。 [由基因组资源联盟提供，2022 年 4 月]

Involved in positive regulation of cell population proliferation. Located in cytoplasm and extracellular region. [provided by Alliance of Genome Resources, Apr 2022]

MZB1 基因产物(1)

mRNA Protein Name
NM_016459.4 NP_057543.2 marginal zone B- and B1-cell-specific protein precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
11350957 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in positive regulation of cell population proliferation IDA
IDA: 通过直接分析推断
21688198 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
11350957 GOA
located in extracellular region IDA
IDA: 通过直接分析推断
21688198 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

MZB1 蛋白结构

DUF3456

DUF3456: TLR4 regulator and MIR-interacting MSAP (49 - 178)

  • 0
  • 100
  • 189 a.a.
蛋白主名 其他名称

marginal zone B- and B1-cell-specific protein

HSPC190

MZB1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
MZB1 Q8WU39 TSG101 Homo sapiens Q99816
Validated Y2H
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

重组 MZB1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P77094 MZB1/PERP1 Protein, Human (HEK293, Fc) Q8WU39-1 (D23-T185) ≥95%
HY-P77095 MZB1/PERP1 Protein, Human (HEK293, His) Q8WU39-1 (D23-T185) ≥95%

关联疾病

疾病名称 别名
Mooren'S Ulcer

Mooren Ulcer

Moorens Ulcer
Isolated Growth Hormone Deficiency

Congenital Ighd

Congenital Isolated Gh Deficiency

Congenital Isolated Growth Hormone Deficiency

Non-Acquired Isolated Growth Hormone Deficiency

Pituitary Dwarfism

Dwarfism, Pituitary

Isolated Somatotropin Deficiency

Isolated Congenital Growth Hormone Deficiency

Familial Isolated Growth Hormone Deficiency

Ighd

Dwarfism, Growth Hormone Deficiency

Growth Hormone Deficiency Dwarfism

Isolated Gh Deficiency

Isolated Hgh Deficiency

Isolated Human Growth Hormone Deficiency

Isolated Somatotropin Deficiency Disorder

Dwarfism Pituitary
Gastric Cancer

Stomach Cancer

Gastric Carcinoma

Stomach Carcinoma

Gastric Cancer, Somatic

Gastric Neoplasm

Carcinoma Of Stomach

Stomach Neoplasms

Malignant Neoplasm Of Stomach

Gastric Cancer Risk After H. Pylori Infection

Cancer Of The Stomach

Adult Stomach Cancer

Adult Stomach Carcinoma

GASC

Gastric Cancer Intestinal

Gastric Cancers

Gastric Carcinomas

Cancer, Gastric

Stomach Neoplasm

Malignant Neoplasm Of Body Of Stomach

Malignant Tumor Of Lesser Curve Of Stomach

Gastrocarcinoma Of Unspecified Site

Leather Bottle Stomach

Carcinoma Of Fundus Of Stomach

Cancer Of Fundus Of Stomach

Primary Malignant Neoplasm Of Body Of Stomach

Cancer Of Body Of Stomach

Primary Malignant Neoplasm Of Pyloric Antrum

Pyloric Antrum Cancer

Malignant Tumour Of Stomach
Chromosome 22q11.2 Deletion Syndrome, Distal

22q11.2 Deletion Syndrome

Autosomal Dominant Opitz G/Bbb Syndrome

Catch22

Cayler Cardiofacial Syndrome

Conotruncal Anomaly Face Syndrome

Digeorge Syndrome

Sedlackova Syndrome

Shprintzen Syndrome

Velocardiofacial Syndrome

22q11.2 Distal Deletion Syndrome

Distal 22q11.2 Microdeletion Syndrome

22q11.2ds

Vcfs

Velo-Cardio-Facial Syndrome

Distal Chromosome 22q11.2 Deletion Syndrome

Chromosome 22q11.2 Deletion Syndrome Distal

Chromosome 22q11.2 Deletion Syndrome

Deletion 22q11.2 Syndrome

22q11ds

Catch 22

Digeorge Sequence

Microdeletion 22q11.2

Monosomy 22q11

Takao Syndrome

Distal Del(22)(Q11.2)

Distal Monosomy 22q11.2

Catch 22 Syndrome

Chromosome Deletion Syndrome 22q11.2, Distal
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS08976 MZB1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Canis familiaris MZB1 VGNC VGNC:43593
Felis catus MZB1 VGNC VGNC:63699
Mus musculus MZB1 MGD MGI:1917066
Rattus norvegicus MZB1 RGD RGD:1310251
Bos taurus MZB1 VGNC VGNC:31849
Macaca mulatta MZB1 VGNC VGNC:110450
Others MZB1 NCBI
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