2. Gene
  3. AMZ2 - archaelysin family metallopeptidase 2 Gene

AMZ2 - archaelysin family metallopeptidase 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：古溶素家族金属肽酶 2

种属: Homo sapiens

基因 ID: 51321 | 基因类型: protein coding

关于 AMZ2

Cytogenetic location: 17q24.2 Genomic coordinates (GRCh38): 17:68,206,129-68,257,164 (from NCBI)

This gene has 20 transcripts (splice variants), 169 orthologues and 1 paralogue. Broad expression in testis (RPKM 44.9), brain (RPKM 18.1) and 25 other tissues.

功能概要

该基因编码的蛋白质是一种锌金属蛋白酶，对血管紧张素 3 具有一定的活性。编码的蛋白质被氨肽酶抑制剂阿姆他汀以及一般抑制剂 o-phenanthroline 和 batimastat 抑制。该基因的缺陷可能与肺肿瘤发生有关。[RefSeq 提供，2016 年 10 月]

The protein encoded by this gene is a zinc metalloprotease that displays some activity against angiotensin-3. The encoded protein is inhibited by the Aminopeptidase Inhibitor amastatin, as well as by the general inhibitors o-phenanthroline and batimastat. Defects in this gene may be associated with lung tumorigenesis. [provided by RefSeq, Oct 2016]

AMZ2 基因产物(23)

mRNA Protein Name
NM_001033569.2 NP_001028741.1 archaemetzincin-2 isoform 1
NM_001033570.2 NP_001028742.1 archaemetzincin-2 isoform 1
NM_001033571.1 NP_001028743.1 archaemetzincin-2 isoform 1
NM_001033572.1 NP_001028744.1 archaemetzincin-2 isoform 1
NM_001033574.2 NP_001028746.1 archaemetzincin-2 isoform 2
NM_001289054.2 NP_001275983.1 archaemetzincin-2 isoform 1
NM_001289056.2 NP_001275985.1 archaemetzincin-2 isoform 1
NM_001346471.1 NP_001333400.1 archaemetzincin-2 isoform 1
NM_001346472.1 NP_001333401.1 archaemetzincin-2 isoform 1
NM_001346473.1 NP_001333402.1 archaemetzincin-2 isoform 1
NM_001346474.2 NP_001333403.1 archaemetzincin-2 isoform 1
NM_001346475.2 NP_001333404.1 archaemetzincin-2 isoform 1
NM_001346476.2 NP_001333405.1 archaemetzincin-2 isoform 1
NM_001346477.2 NP_001333406.1 archaemetzincin-2 isoform 1
NM_001346478.2 NP_001333407.1 archaemetzincin-2 isoform 1
NM_001346479.2 NP_001333408.1 archaemetzincin-2 isoform 1
NM_001346480.1 NP_001333409.1 archaemetzincin-2 isoform 2
NM_001346481.1 NP_001333410.1 archaemetzincin-2 isoform 3
NM_001346482.1 NP_001333411.1 archaemetzincin-2 isoform 3
NM_001346483.2 NP_001333412.1 archaemetzincin-2 isoform 3
NM_001346484.2 NP_001333413.1 archaemetzincin-2 isoform 3
NM_001346485.2 NP_001333414.1 archaemetzincin-2 isoform 4
NM_016627.5 NP_057711.3 archaemetzincin-2 isoform 1

AMZ2 蛋白结构

Peptidase_M54

Peptidase_M54: Peptidase family M54 (233 - 297)

  • 0
  • 100
  • 200
  • 300
  • 360 a.a.
蛋白主名 其他名称

archaemetzincin-2

archaemetzincins-2

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS00676 AMZ2 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus AMZ2 RGD RGD:1304846
Bos taurus AMZ2 VGNC VGNC:25878
Felis catus AMZ2 VGNC VGNC:97348
Canis familiaris AMZ2 VGNC VGNC:37843
Mus musculus AMZ2 MGD MGI:104837
Macaca mulatta AMZ2 VGNC VGNC:104568
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