2. Gene
  3. TRAPPC4 - trafficking protein particle complex subunit 4 Gene

TRAPPC4 - trafficking protein particle complex subunit 4 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：运输蛋白颗粒复合物亚基 4

种属: Homo sapiens

同用名: SBDN; TRS23; PTD009; CGI-104; HSPC172; NEDESBA; SYNBINDIN

基因 ID: 51399 | 基因类型: protein coding

关于 TRAPPC4

Cytogenetic location: 11q23.3 Genomic coordinates (GRCh38): 11:119,018,766-119,024,134 (from NCBI)

This gene has 14 transcripts (splice variants), 1 gene allele, 214 orthologues, 1 paralogue and is associated with 3 phenotypes. Ubiquitous expression in testis (RPKM 25.2), adrenal (RPKM 22.1) and 25 other tissues.

功能概要

参与自噬和内质网向高尔基体囊泡介导的转运。 TRAPP 综合体的一部分。 [由基因组资源联盟提供，2022 年 4 月]

Involved in Autophagy and endoplasmic reticulum to Golgi vesicle-mediated transport. Part of TRAPP complex. [provided by Alliance of Genome Resources, Apr 2022]

TRAPPC4 基因产物(7)

mRNA Protein Name
NM_001318486.2 NP_001305415.1 trafficking protein particle complex subunit 4 isoform 2 precursor
NM_001318488.2 NP_001305417.1 trafficking protein particle complex subunit 4 isoform 3
NM_001318489.2 NP_001305418.1 trafficking protein particle complex subunit 4 isoform 4
NM_001318490.2 NP_001305419.1 trafficking protein particle complex subunit 4 isoform 5
NM_001318492.2 NP_001305421.1 trafficking protein particle complex subunit 4 isoform 6
NM_001318494.2 NP_001305423.1 trafficking protein particle complex subunit 4 isoform 7
NM_016146.6 NP_057230.1 trafficking protein particle complex subunit 4 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
17110339 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in autophagy IMP
IMP: 通过突变表型推断
31794024 GOA
involved in endoplasmic reticulum to Golgi vesicle-mediated transport IMP
IMP: 通过突变表型推断
31794024 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of TRAPP complex IDA
IDA: 通过直接分析推断
21525244 GOA
part of TRAPP complex IMP
IMP: 通过突变表型推断
31794024 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

TRAPPC4 蛋白结构

Sybindin

Sybindin: Sybindin-like family (3 - 207)

  • 0
  • 100
  • 200
  • 219 a.a.
蛋白主名 其他名称

trafficking protein particle complex subunit 4

TRS23 homolog

关联疾病

疾病名称 别名
Neurodevelopmental Disorder With Epilepsy, Spasticity, And Brain Atrophy

NEDESBA
Neurodevelopmental Disorder With Progressive Microcephaly, Spasticity, And Brain Anomalies

NDMSBA

Plaa-Associated Neurodevelopmental Disorder

Plaand
Non-Specific Syndromic Intellectual Disability

Complex Neurodevelopmental Disorder
Spondyloepiphyseal Dysplasia Tarda, X-Linked

Spondyloepiphyseal Dysplasia Tarda

X-Linked Spondyloepiphyseal Dysplasia Tarda

SEDT

Sed Tarda, X-Linked

Spondyloepiphyseal Dysplasia, Late

Spondyloepiphyseal Dysplasia Tarda X-Linked

Sed

X Linked Spondyloepiphyseal Dysplasia Tarda

X-Linked Spondyloepiphyseal Dysplasia

Late Onset Spondyloepiphyseal Dysplasia

Sed Tarda

X-Linked Sed

X-Linked Sedt

Dysplasia, Spondyloepiphyseal, Tarda

Spondyloepiphyseal Dysplasia
Neu-Laxova Syndrome 2

NLS2
Microcephaly

Microencephaly

Microcephalus

Microcephalic

Nanocephaly

Congenital Microcephaly

Brain Hypoplasia

Brain Nondevelopment

Cephalic Hypoplasia

Undeveloped Cerebrum

Undeveloped Brain

Micrencephalon

Micrencephaly
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS14991 TRAPPC4 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus TRAPPC4 MGD MGI:1926211
Felis catus TRAPPC4 VGNC VGNC:66513
Bos taurus TRAPPC4 VGNC VGNC:36290
Rattus norvegicus TRAPPC4 RGD RGD:1302991
Canis familiaris TRAPPC4 VGNC VGNC:47783
Macaca mulatta TRAPPC4 VGNC VGNC:79211
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