1. Gene
  2. SERPINB10 - serpin family B member 10 Gene

SERPINB10 - serpin family B member 10 Gene

中文名称:serpin 家族 B 成员 10

种属: Homo sapiens

同用名: PI10; PI-10

基因 ID: 5273 | 基因类型: protein coding

关于 SERPINB10

Cytogenetic location: 18q22.1 Genomic coordinates (GRCh38): 18:63,907,958-63,936,111 (from NCBI)

This gene has 1 transcript (splice variant), 122 orthologues and 36 paralogues. Restricted expression toward bone marrow (RPKM 23.0).

功能概要

该基因是 serpin 肽酶抑制剂 B 进化枝家族的一员,存在于 18 号染色体上的一组其他类似基因中。该基因编码的蛋白质似乎有助于控制造血过程中蛋白酶功能的调节。该基因的变异可能会增加患前列腺癌的风险。[RefSeq 提供,2015 年 12 月]

This gene is a member of the serpin peptidase inhibitor, clade B family and is found in a cluster of Other similar genes on chromosome 18. The protein encoded by this gene appears to help control the regulation of protease functions during hematopoiesis. Variations in this gene may increase the risk of prostate Cancer. [provided by RefSeq, Dec 2015]

SERPINB10 基因产物(1)

mRNA Protein Name
NM_005024.3 NP_005015.1 serpin B10

SERPINB10 蛋白结构

Serpin

Serpin: Serpin (serine protease inhibitor) (7 - 397)

  • 0
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  • 200
  • 300
  • 397 a.a.
蛋白主名 其他名称

serpin B10

bomapin

关联疾病

疾病名称 别名
Tracheal Calcification

Calcification Of Trachea

Chronic Myelomonocytic Leukemia

Leukemia, Myelomonocytic, Chronic

Cmml

Leukemia Myelomonocytic Chronic

Cmml - [Chronic Myelomonocytic Leukaemia]

Chronic Myelomonocytic Leukaemia Without Mention Of Remission

Chronic Monocytic Leukaemia

Chronic Monocytoid Leukaemia

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus SERPINB10 RGD RGD:628853
Canis familiaris SERPINB10 VGNC VGNC:46027
Felis catus SERPINB10 VGNC VGNC:68833
Mus musculus SERPINB10 MGD MGI:2138648
Macaca mulatta SERPINB10 VGNC VGNC:77365
Bos taurus SERPINB10 VGNC VGNC:56372
Others SERPINB10 NCBI