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  3. PPA1 - inorganic pyrophosphatase 1 Gene

PPA1 - inorganic pyrophosphatase 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：无机焦磷酸酶 1

种属: Homo sapiens

同用名: PP; PP1; IOPPP; HEL-S-66p; SID6-8061

基因 ID: 5464 | 基因类型: protein coding

关于 PPA1

Cytogenetic location: 10q22.1 Genomic coordinates (GRCh38): 10:70,202,835-70,233,429 (from NCBI)

This gene has 6 transcripts (splice variants), 284 orthologues and 1 paralogue. Ubiquitous expression in adrenal (RPKM 81.3), colon (RPKM 70.8) and 25 other tissues.

功能概要

该基因编码的蛋白质是无机焦磷酸酶 (PPase) 家族的成员。 PPases 催化焦磷酸盐水解成无机磷酸盐，这对细胞的磷酸盐代谢很重要。对牛中类似蛋白质的研究表明该酶定位于细胞质。[RefSeq 提供，2008 年 7 月]

The protein encoded by this gene is a member of the inorganic pyrophosphatase (PPase) family. PPases catalyze the hydrolysis of pyrophosphate to inorganic phosphate, which is important for the phosphate metabolism of cells. Studies of a similar protein in bovine suggested a cytoplasmic localization of this Enzyme. [provided by RefSeq, Jul 2008]

PPA1 基因产物(1)

mRNA Protein Name
NM_021129.4 NP_066952.1 inorganic pyrophosphatase

PPA1 蛋白结构

Pyrophosphatase

Pyrophosphatase: Inorganic pyrophosphatase (45 - 228)

  • 0
  • 100
  • 200
  • 289 a.a.
蛋白主名 其他名称

inorganic pyrophosphatase

PPase

PPA1 抗体

目录号 产品名 应用 反应物种
HY-P82041 Pyrophosphatase 1 Antibody (YA1786) WB, IP Human, Mouse

关联疾病

疾病名称 别名
Baylisascariasis

Infection By Baylisascaris
Hypophosphatasia, Adult

Adult Hypophosphatasia

Odontohypophosphatasia

Hypophosphatasia, Mild

HPPA

Hypophosphatasia

Mild Hypophosphatasia

Adult Rathbun Disease

Adult Phosphoethanolaminuria

HOPS
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P4072A (D)-PPA 1 TFA Inhibitor 99.84% 否
HY-P4072 (D)-PPA 1 Inhibitor / 否
HY-RS10914 PPA1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus PPA1 VGNC VGNC:55992
Macaca mulatta PPA1 VGNC VGNC:103845
Canis familiaris PPA1 VGNC VGNC:81244
Felis catus PPA1 VGNC VGNC:96709
Mus musculus PPA1 MGD MGI:97831
Rattus norvegicus PPA1 RGD RGD:1589773
Others PPA1 NCBI
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